| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AFZ71674.1 | AFZ72254.1 | Natgr_0419 | Natgr_1023 | Putative metal-dependent protease of the PAD1/JAB1 superfamily. | Trypsin-like serine protease with C-terminal PDZ domain; PFAM: Trypsin. | 0.521 |
| AFZ71674.1 | AFZ73397.1 | Natgr_0419 | Natgr_2220 | Putative metal-dependent protease of the PAD1/JAB1 superfamily. | Trypsin-like serine protease with C-terminal PDZ domain; PFAM: Trypsin. | 0.521 |
| AFZ71674.1 | pan | Natgr_0419 | Natgr_0854 | Putative metal-dependent protease of the PAD1/JAB1 superfamily. | 26S proteasome subunit P45 family; ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C- termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes ATPase-2 [...] | 0.868 |
| AFZ71674.1 | pan-2 | Natgr_0419 | Natgr_1970 | Putative metal-dependent protease of the PAD1/JAB1 superfamily. | 26S proteasome subunit P45 family; ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C- termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes ATPase-2 [...] | 0.868 |
| AFZ71674.1 | psmA | Natgr_0419 | Natgr_3644 | Putative metal-dependent protease of the PAD1/JAB1 superfamily. | Proteasome endopeptidase complex, archaeal, alpha subunit; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. | 0.774 |
| AFZ71674.1 | psmB | Natgr_0419 | Natgr_3623 | Putative metal-dependent protease of the PAD1/JAB1 superfamily. | Proteasome endopeptidase complex, archaeal, beta subunit; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. | 0.774 |
| AFZ71674.1 | rpl40e | Natgr_0419 | Natgr_1147 | Putative metal-dependent protease of the PAD1/JAB1 superfamily. | PFAM: Ribosomal L40e family; Belongs to the eukaryotic ribosomal protein eL40 family. | 0.923 |
| AFZ71674.1 | rps11p | Natgr_0419 | Natgr_2553 | Putative metal-dependent protease of the PAD1/JAB1 superfamily. | Archaeal ribosomal protein S11P; Located on the platform of the 30S subunit. Belongs to the universal ribosomal protein uS11 family. | 0.727 |
| AFZ71674.1 | rps5p | Natgr_0419 | Natgr_0295 | Putative metal-dependent protease of the PAD1/JAB1 superfamily. | Ribosomal protein S5/S2; With S4 and S12 plays an important role in translational accuracy. | 0.765 |
| AFZ72254.1 | AFZ71674.1 | Natgr_1023 | Natgr_0419 | Trypsin-like serine protease with C-terminal PDZ domain; PFAM: Trypsin. | Putative metal-dependent protease of the PAD1/JAB1 superfamily. | 0.521 |
| AFZ72254.1 | AFZ73350.1 | Natgr_1023 | Natgr_2171 | Trypsin-like serine protease with C-terminal PDZ domain; PFAM: Trypsin. | Putative metal-dependent protease of the PAD1/JAB1 superfamily; PFAM: Mov34/MPN/PAD-1 family. | 0.521 |
| AFZ72254.1 | AFZ73397.1 | Natgr_1023 | Natgr_2220 | Trypsin-like serine protease with C-terminal PDZ domain; PFAM: Trypsin. | Trypsin-like serine protease with C-terminal PDZ domain; PFAM: Trypsin. | 0.905 |
| AFZ72254.1 | pan | Natgr_1023 | Natgr_0854 | Trypsin-like serine protease with C-terminal PDZ domain; PFAM: Trypsin. | 26S proteasome subunit P45 family; ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C- termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes ATPase-2 [...] | 0.710 |
| AFZ72254.1 | pan-2 | Natgr_1023 | Natgr_1970 | Trypsin-like serine protease with C-terminal PDZ domain; PFAM: Trypsin. | 26S proteasome subunit P45 family; ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C- termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes ATPase-2 [...] | 0.710 |
| AFZ72254.1 | psmA | Natgr_1023 | Natgr_3644 | Trypsin-like serine protease with C-terminal PDZ domain; PFAM: Trypsin. | Proteasome endopeptidase complex, archaeal, alpha subunit; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. | 0.505 |
| AFZ72254.1 | psmB | Natgr_1023 | Natgr_3623 | Trypsin-like serine protease with C-terminal PDZ domain; PFAM: Trypsin. | Proteasome endopeptidase complex, archaeal, beta subunit; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. | 0.505 |
| AFZ73350.1 | AFZ72254.1 | Natgr_2171 | Natgr_1023 | Putative metal-dependent protease of the PAD1/JAB1 superfamily; PFAM: Mov34/MPN/PAD-1 family. | Trypsin-like serine protease with C-terminal PDZ domain; PFAM: Trypsin. | 0.521 |
| AFZ73350.1 | AFZ73397.1 | Natgr_2171 | Natgr_2220 | Putative metal-dependent protease of the PAD1/JAB1 superfamily; PFAM: Mov34/MPN/PAD-1 family. | Trypsin-like serine protease with C-terminal PDZ domain; PFAM: Trypsin. | 0.521 |
| AFZ73350.1 | pan | Natgr_2171 | Natgr_0854 | Putative metal-dependent protease of the PAD1/JAB1 superfamily; PFAM: Mov34/MPN/PAD-1 family. | 26S proteasome subunit P45 family; ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C- termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes ATPase-2 [...] | 0.868 |
| AFZ73350.1 | pan-2 | Natgr_2171 | Natgr_1970 | Putative metal-dependent protease of the PAD1/JAB1 superfamily; PFAM: Mov34/MPN/PAD-1 family. | 26S proteasome subunit P45 family; ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C- termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes ATPase-2 [...] | 0.868 |
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