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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AFZ72126.1ACT-domain-containing protein, predicted allosteric regulator of homoserine dehydrogenase. (187 aa)    
Predicted Functional Partners:
AFZ72127.1
Homoserine dehydrogenase; PFAM: Glutamate/Leucine/Phenylalanine/Valine dehydrogenase; Homoserine dehydrogenase.
       0.836
AFZ72801.1
PFAM: Uncharacterized protein conserved in archaea (DUF2073).
  
     0.729
rnp3
RNase P/RNase MRP subunit p30; Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends; Belongs to the eukaryotic/archaeal RNase P protein component 3 family.
  
     0.717
AFZ74884.1
PFAM: Protein of unknown function (DUF447).
  
     0.716
cofC
2-phospho-L-lactate guanylyltransferase; Guanylyltransferase that catalyzes the activation of phosphoenolpyruvate (PEP) as enolpyruvoyl-2-diphospho-5'-guanosine, via the condensation of PEP with GTP. It is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor; Belongs to the CofC family.
  
     0.714
AFZ71445.1
Putative transcriptional regulator, contains C-terminal CBS domains; PFAM: Domain of unknown function.
  
     0.708
AFZ71757.1
Archaeal flagella assembly protein J; PFAM: Bacterial type II secretion system protein F domain.
  
     0.705
AFZ74883.1
Triphosphoribosyl-dephospho-CoA synthetase; PFAM: ATP:dephospho-CoA triphosphoribosyl transferase.
  
     0.695
AFZ71884.1
PFAM: Protein of unknown function (DUF1628); TIGRFAM: archaeal flagellin N-terminal-like domain.
  
     0.693
AFZ71421.1
PFAM: Protein of unknown function (DUF1628); TIGRFAM: archaeal flagellin N-terminal-like domain.
  
     0.691
Your Current Organism:
Natronobacterium gregoryi
NCBI taxonomy Id: 797304
Other names: N. gregoryi SP2, Natronobacterium gregoryi ATCC 43098, Natronobacterium gregoryi JCM 8860, Natronobacterium gregoryi NCIMB 2189, Natronobacterium gregoryi SP2, Natronobacterium gregoryi str. SP2, Natronobacterium gregoryi strain SP2
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