Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AFZ72194.1NTP pyrophosphohydrolase; PFAM: NUDIX domain. (144 aa)    
Predicted Functional Partners:
rps10
Ribosomal protein S10; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family.
       0.854
AFZ72196.1
Hypothetical protein.
       0.837
flpA
Fibrillarin-like rRNA methylase; Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA; Belongs to the methyltransferase superfamily. Fibrillarin family.
  
 0.605
AFZ72195.1
Hypothetical protein.
       0.536
AFZ73879.1
PFAM: RNB domain; TIGRFAM: VacB and RNase II family 3'-5' exoribonucleases.
   
 0.482
AFZ72192.1
Amidohydrolase; PFAM: Peptidase family M20/M25/M40; Peptidase dimerisation domain; TIGRFAM: amidohydrolase.
       0.436
AFZ72254.1
Trypsin-like serine protease with C-terminal PDZ domain; PFAM: Trypsin.
 
  
  0.419
AFZ72732.1
PFAM: Tetratricopeptide repeat.
 
 
 0.412
AFZ73397.1
Trypsin-like serine protease with C-terminal PDZ domain; PFAM: Trypsin.
 
  
  0.412
AFZ74509.1
Putative acyl-CoA transferase/carnitine dehydratase; PFAM: CoA-transferase family III.
  
 
  0.401
Your Current Organism:
Natronobacterium gregoryi
NCBI taxonomy Id: 797304
Other names: N. gregoryi SP2, Natronobacterium gregoryi ATCC 43098, Natronobacterium gregoryi JCM 8860, Natronobacterium gregoryi NCIMB 2189, Natronobacterium gregoryi SP2, Natronobacterium gregoryi str. SP2, Natronobacterium gregoryi strain SP2
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