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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AFZ72223.1PFAM: Pyridoxamine 5'-phosphate oxidase; TIGRFAM: PPOX class probable F420-dependent enzyme. (133 aa)    
Predicted Functional Partners:
AFZ74083.1
PFAM: Luciferase-like monooxygenase; TIGRFAM: coenzyme F420-dependent oxidoreductase, NP1902A family.
  
     0.683
AFZ72784.1
Flavin-dependent oxidoreductase, F420-dependent methylene-tetrahydromethanopterin reductase; PFAM: Luciferase-like monooxygenase.
  
     0.655
AFZ71281.1
PFAM: Luciferase-like monooxygenase; TIGRFAM: coenzyme F420-dependent oxidoreductase, NP1902A family; probable F420-dependent oxidoreductase, Rv3520c family.
  
     0.650
cofD
LPPG:FO 2-phospho-L-lactate transferase; Catalyzes the transfer of the phosphoenolpyruvate moiety from enoylpyruvoyl-2-diphospho-5'-guanosine (EPPG) to 7,8-didemethyl-8- hydroxy-5-deazariboflavin (FO) with the formation of dehydro coenzyme F420-0 and GMP.
  
     0.641
cofE
F420-0:gamma-glutamyl ligase; Catalyzes the GTP-dependent successive addition of two or more gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8- didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form coenzyme F420- 0-glutamyl-glutamate (F420-2) or polyglutamated F420 derivatives.
  
     0.632
cofG
7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase, CofG subunit; Catalyzes the radical-mediated synthesis of 7,8-didemethyl-8- hydroxy-5-deazariboflavin (FO) from 5-amino-5-(4-hydroxybenzyl)-6-(D- ribitylimino)-5,6-dihydrouracil.
  
     0.554
npdG
PFAM: NADP oxidoreductase coenzyme F420-dependent; TIGRFAM: NADPH-dependent F420 reductase.
  
     0.550
AFZ72222.1
PFAM: Predicted membrane-bound metal-dependent hydrolase (DUF457).
       0.498
AFZ72221.1
Hypothetical protein.
       0.492
mer
Flavin-dependent oxidoreductase, F420-dependent methylene-tetrahydromethanopterin reductase; Catalyzes the oxidation of methyl-H(4)MPT to methylene- H(4)MPT.
  
     0.447
Your Current Organism:
Natronobacterium gregoryi
NCBI taxonomy Id: 797304
Other names: N. gregoryi SP2, Natronobacterium gregoryi ATCC 43098, Natronobacterium gregoryi JCM 8860, Natronobacterium gregoryi NCIMB 2189, Natronobacterium gregoryi SP2, Natronobacterium gregoryi str. SP2, Natronobacterium gregoryi strain SP2
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