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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AFZ72331.1PFAM: E3 Ubiquitin ligase. (248 aa)    
Predicted Functional Partners:
AFZ72330.1
PFAM: Uncharacterized conserved protein (DUF2267).
 
     0.701
AFZ73003.1
Ribonuclease HI; PFAM: RNase H.
  
     0.615
AFZ72485.1
PFAM: EthD protein; TIGRFAM: conserved hypothetical protein.
  
     0.609
AFZ72332.1
Putative TIM-barrel fold metal-dependent hydrolase; PFAM: Amidohydrolase family.
       0.604
AFZ71284.1
PFAM: PAP2 superfamily.
  
     0.601
AFZ73125.1
PFAM: Flagella accessory protein C (FlaC); Archaeal flagella protein.
  
     0.599
AFZ73558.1
Putative lipoprotein involved in nitrous oxide reduction; PFAM: NosL.
  
     0.587
AFZ71866.1
Membrane-associated phospholipid phosphatase; PFAM: PAP2 superfamily.
  
     0.572
AFZ71868.1
PFAM: PAP2 superfamily.
  
     0.571
AFZ73114.1
HEAT repeat-containing protein; PFAM: PBS lyase HEAT-like repeat; HEAT repeat.
  
     0.535
Your Current Organism:
Natronobacterium gregoryi
NCBI taxonomy Id: 797304
Other names: N. gregoryi SP2, Natronobacterium gregoryi ATCC 43098, Natronobacterium gregoryi JCM 8860, Natronobacterium gregoryi NCIMB 2189, Natronobacterium gregoryi SP2, Natronobacterium gregoryi str. SP2, Natronobacterium gregoryi strain SP2
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