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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
tfxPFAM: Sigma-70, region 4; TIGRFAM: DNA-binding protein, Tfx family. (152 aa)    
Predicted Functional Partners:
AFZ72126.1
ACT-domain-containing protein, predicted allosteric regulator of homoserine dehydrogenase.
  
     0.668
AFZ73516.1
Putative metal-binding protein.
 
     0.623
AFZ72384.1
Zn-dependent hydrolase, glyoxylase; PFAM: Metallo-beta-lactamase superfamily.
 
     0.594
AFZ73527.1
PFAM: Uncharacterised protein family (UPF0146); manually curated; Belongs to the UPF0146 family.
  
     0.582
AFZ71757.1
Archaeal flagella assembly protein J; PFAM: Bacterial type II secretion system protein F domain.
  
     0.574
AFZ71445.1
Putative transcriptional regulator, contains C-terminal CBS domains; PFAM: Domain of unknown function.
  
    0.552
cofC
2-phospho-L-lactate guanylyltransferase; Guanylyltransferase that catalyzes the activation of phosphoenolpyruvate (PEP) as enolpyruvoyl-2-diphospho-5'-guanosine, via the condensation of PEP with GTP. It is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor; Belongs to the CofC family.
  
     0.526
AFZ71463.1
PFAM: Membrane protein of unknown function DUF63.
  
     0.507
rnp3
RNase P/RNase MRP subunit p30; Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends; Belongs to the eukaryotic/archaeal RNase P protein component 3 family.
  
     0.503
AFZ72414.1
Hypothetical protein.
  
     0.500
Your Current Organism:
Natronobacterium gregoryi
NCBI taxonomy Id: 797304
Other names: N. gregoryi SP2, Natronobacterium gregoryi ATCC 43098, Natronobacterium gregoryi JCM 8860, Natronobacterium gregoryi NCIMB 2189, Natronobacterium gregoryi SP2, Natronobacterium gregoryi str. SP2, Natronobacterium gregoryi strain SP2
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