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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mptATIGR00294 family protein; Converts GTP to 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate, the first intermediate in the biosynthesis of coenzyme methanopterin. (310 aa)    
Predicted Functional Partners:
moaA
Putative molybdenum cofactor biosynthesis protein A, archaeal; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate; Belongs to the radical SAM superfamily. MoaA family.
     
  0.900
pyk
PFAM: Pyruvate kinase, barrel domain; PEP-utilising enzyme, mobile domain; Pyruvate kinase, alpha/beta domain; TIGRFAM: pyruvate kinase; Belongs to the pyruvate kinase family.
 
  
  0.843
ndk
Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
    
  0.801
cyaB
PFAM: CYTH domain; TIGRFAM: adenylyl cyclase CyaB, putative.
     
  0.800
AFZ74424.1
PFAM: 6-pyruvoyl tetrahydropterin synthase.
    
 0.640
mptD
Hypothetical protein; Catalyzes the conversion of 7,8-dihydroneopterin (H2Neo) to 6-hydroxymethyl-7,8-dihydropterin (6-HMD); Belongs to the archaeal dihydroneopterin aldolase family.
 
   
 0.632
AFZ72320.1
Putative GTPase, G3E family; PFAM: CobW/HypB/UreG, nucleotide-binding domain; Cobalamin synthesis protein cobW C-terminal domain.
  
  
 0.622
AFZ72517.1
Putative GTPase, G3E family; PFAM: Cobalamin synthesis protein cobW C-terminal domain; CobW/HypB/UreG, nucleotide-binding domain.
  
  
 0.622
AFZ72518.1
Putative GTPase, G3E family; PFAM: Cobalamin synthesis protein cobW C-terminal domain; CobW/HypB/UreG, nucleotide-binding domain.
  
  
 0.622
AFZ74696.1
Putative GTPase, G3E family; PFAM: Cobalamin synthesis protein cobW C-terminal domain; CobW/HypB/UreG, nucleotide-binding domain.
  
  
 0.622
Your Current Organism:
Natronobacterium gregoryi
NCBI taxonomy Id: 797304
Other names: N. gregoryi SP2, Natronobacterium gregoryi ATCC 43098, Natronobacterium gregoryi JCM 8860, Natronobacterium gregoryi NCIMB 2189, Natronobacterium gregoryi SP2, Natronobacterium gregoryi str. SP2, Natronobacterium gregoryi strain SP2
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