close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AFZ72442.1PFAM: Proline dehydrogenase. (306 aa)    
Predicted Functional Partners:
proC
Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
   
 0.937
AFZ73627.1
PFAM: Proline dehydrogenase.
  
  
 
0.903
AFZ74314.1
PFAM: Sodium:solute symporter family; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
 
  
 0.718
AFZ72116.1
PFAM: Sodium:solute symporter family; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
  
  
 0.681
AFZ74812.1
PFAM: Citrate synthase; TIGRFAM: 2-methylcitrate synthase/citrate synthase II.
  
  
 0.667
AFZ71402.1
Heme/copper-type cytochrome/quinol oxidase, subunit 1; PFAM: Cytochrome c oxidase subunit III; Cytochrome C and Quinol oxidase polypeptide I; Belongs to the heme-copper respiratory oxidase family.
 
 
 
 0.619
AFZ72443.1
Hypothetical protein.
       0.596
AFZ72788.1
acyl-CoA synthetase/AMP-acid ligase; PFAM: AMP-binding enzyme.
 
  
 0.581
AFZ74693.1
PFAM: Carbon starvation protein CstA.
   
  
 0.540
AFZ73818.1
PFAM: Aldehyde dehydrogenase family.
 
 
 0.531
Your Current Organism:
Natronobacterium gregoryi
NCBI taxonomy Id: 797304
Other names: N. gregoryi SP2, Natronobacterium gregoryi ATCC 43098, Natronobacterium gregoryi JCM 8860, Natronobacterium gregoryi NCIMB 2189, Natronobacterium gregoryi SP2, Natronobacterium gregoryi str. SP2, Natronobacterium gregoryi strain SP2
Server load: low (36%) [HD]