close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
paaDPhenylacetic acid degradation protein PaaD; PFAM: Thioesterase superfamily; TIGRFAM: uncharacterized domain 1; phenylacetic acid degradation protein PaaD. (131 aa)    
Predicted Functional Partners:
paaA
Hypothetical protein; PFAM: Phenylacetic acid catabolic protein; TIGRFAM: phenylacetate-CoA oxygenase, PaaG subunit.
 
 
 0.985
paaI
PFAM: Phenylacetic acid catabolic protein; TIGRFAM: phenylacetate-CoA oxygenase, PaaI subunit.
 
 
 0.984
AFZ72469.1
Putative enzyme of phenylacetate metabolism; PFAM: Phenylacetic acid degradation B; TIGRFAM: phenylacetate-CoA oxygenase, PaaH subunit.
 
  
  0.978
AFZ72460.1
Coenzyme F390 synthetase; PFAM: AMP-binding enzyme.
 
 
 0.954
AFZ74729.1
Amidase, Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit; PFAM: Amidase.
    
  0.901
AFZ74295.1
PFAM: Acetamidase/Formamidase family.
     
  0.900
AFZ72471.1
Putative metal-sulfur cluster biosynthetic enzyme; PFAM: Domain of unknown function DUF59; TIGRFAM: phenylacetate-CoA oxygenase, PaaJ subunit.
 
  
 0.665
AFZ72467.1
PFAM: HTH DNA binding domain.
       0.651
purA
Adenylosuccinate synthase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.
  
    0.500
AFZ72472.1
Hypothetical protein.
       0.464
Your Current Organism:
Natronobacterium gregoryi
NCBI taxonomy Id: 797304
Other names: N. gregoryi SP2, Natronobacterium gregoryi ATCC 43098, Natronobacterium gregoryi JCM 8860, Natronobacterium gregoryi NCIMB 2189, Natronobacterium gregoryi SP2, Natronobacterium gregoryi str. SP2, Natronobacterium gregoryi strain SP2
Server load: low (30%) [HD]