STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AFZ72503.1Nicotinamidase-like amidase; PFAM: Isochorismatase family. (192 aa)    
Predicted Functional Partners:
AFZ72505.1
Nicotinic acid phosphoribosyltransferase; PFAM: Quinolinate phosphoribosyl transferase, C-terminal domain.
 
  
 0.842
AFZ72504.1
Hypothetical protein.
       0.639
AFZ73819.1
Putative amidohydrolase; PFAM: Carbon-nitrogen hydrolase.
   
 
 0.618
nadE
NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.
  
  
 0.611
nadC
Nicotinate-nucleotide pyrophosphorylase; Involved in the catabolism of quinolinic acid (QA). Belongs to the NadC/ModD family.
  
 
 0.566
AFZ73468.1
Maleate cis-trans isomerase; PFAM: Asp/Glu/Hydantoin racemase.
 
  
 0.566
AFZ73391.1
birA, biotin-(acetyl-CoA-carboxylase) ligase; PFAM: HTH domain; Biotin protein ligase C terminal domain; Biotin/lipoate A/B protein ligase family; TIGRFAM: birA, biotin-[acetyl-CoA-carboxylase] ligase region; BirA biotin operon repressor domain.
     
 0.555
AFZ73826.1
Putative nucleoside-diphosphate sugar epimerase; PFAM: NAD dependent epimerase/dehydratase family.
  
  
 0.551
AFZ73267.1
NAD-dependent protein deacetylase, SIR2 family; PFAM: Sir2 family.
 
 
 0.519
rps12P
Ribosomal protein S23; With S4 and S5 plays an important role in translational accuracy. Located at the interface of the 30S and 50S subunits. Belongs to the universal ribosomal protein uS12 family.
  
  
 0.517
Your Current Organism:
Natronobacterium gregoryi
NCBI taxonomy Id: 797304
Other names: N. gregoryi SP2, Natronobacterium gregoryi ATCC 43098, Natronobacterium gregoryi JCM 8860, Natronobacterium gregoryi NCIMB 2189, Natronobacterium gregoryi SP2, Natronobacterium gregoryi str. SP2, Natronobacterium gregoryi strain SP2
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.