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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AFZ72612.1PFAM: yrdC domain; TIGRFAM: Sua5/YciO/YrdC/YwlC family protein. (194 aa)    
Predicted Functional Partners:
AFZ73290.1
Metallohydrolase, glycoprotease/Kae1 family; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. The Kae1 domain likely plays a direct catalytic role in this reaction. The Bud32 domain probably displays kinase activity that regulates Kae1 function. In the N-terminal section; belongs to the KAE1 / TsaD family.
 
 
 0.908
glyA
Glycine/serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. Also exhibits THF-independent aldolase activity toward beta- hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
    
 0.859
AFZ72613.1
Peroxiredoxin; PFAM: AhpC/TSA family.
     
 0.734
AFZ72614.1
Glutaredoxin-like protein; PFAM: Glutaredoxin.
       0.728
AFZ73323.1
HemK-related putative methylase; PFAM: Methyltransferase small domain; TIGRFAM: HemK-related putative methylase.
  
  
 0.684
ksgA
Dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
 
  
 0.650
AFZ72615.1
CBS domain-containing protein; PFAM: CBS domain; Domain of unknown function DUF21; Transporter associated domain.
       0.594
AFZ73862.1
Histone acetyltransferase, ELP3 family; PFAM: Acetyltransferase (GNAT) family; Radical SAM superfamily; TIGRFAM: histone acetyltransferase, ELP3 family.
  
   0.575
AFZ71735.1
Putative RND superfamily exporter; PFAM: MMPL family.
  
   0.541
AFZ73244.1
Putative RND superfamily exporter; PFAM: MMPL family.
  
   0.541
Your Current Organism:
Natronobacterium gregoryi
NCBI taxonomy Id: 797304
Other names: N. gregoryi SP2, Natronobacterium gregoryi ATCC 43098, Natronobacterium gregoryi JCM 8860, Natronobacterium gregoryi NCIMB 2189, Natronobacterium gregoryi SP2, Natronobacterium gregoryi str. SP2, Natronobacterium gregoryi strain SP2
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