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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AFZ72615.1CBS domain-containing protein; PFAM: CBS domain; Domain of unknown function DUF21; Transporter associated domain. (483 aa)    
Predicted Functional Partners:
AFZ72614.1
Glutaredoxin-like protein; PFAM: Glutaredoxin.
 
     0.711
AFZ72613.1
Peroxiredoxin; PFAM: AhpC/TSA family.
       0.668
folP-2
Dihydropteroate synthase; PFAM: Pterin binding enzyme; Mur ligase family, glutamate ligase domain; Mur ligase middle domain; TIGRFAM: dihydropteroate synthase; folylpolyglutamate synthase/dihydrofolate synthase.
 
  
 0.635
AFZ72612.1
PFAM: yrdC domain; TIGRFAM: Sua5/YciO/YrdC/YwlC family protein.
       0.594
AFZ72225.1
AICAR transformylase/IMP cyclohydrolase PurH; PFAM: AICARFT/IMPCHase bienzyme; Formyl transferase; TIGRFAM: phosphoribosylglycinamide formyltransferase, formyltetrahydrofolate-dependent.
 
   
 0.550
nadK
Inositol monophosphatase/fructose-1,6-bisphosphatase family protein; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
 
    0.511
AFZ72530.1
ABC-type multidrug transport system, ATPase and permease component; PFAM: ABC transporter transmembrane region; ABC transporter.
  
 
 0.488
cdd
Cytidine deaminase, homotetrameric; PFAM: Cytidine and deoxycytidylate deaminase zinc-binding region; TIGRFAM: cytidine deaminase, homotetrameric.
 
    0.469
AFZ71679.1
P-type ATPase, translocating; PFAM: E1-E2 ATPase; Cation transporting ATPase, C-terminus; Cation transporter/ATPase, N-terminus; haloacid dehalogenase-like hydrolase; TIGRFAM: plasma-membrane calcium-translocating P-type ATPase; ATPase, P-type (transporting), HAD superfamily, subfamily IC.
  
 
 0.469
cysS
PFAM: tRNA synthetases class I (C) catalytic domain; DALR domain; TIGRFAM: cysteinyl-tRNA synthetase.
 
    0.456
Your Current Organism:
Natronobacterium gregoryi
NCBI taxonomy Id: 797304
Other names: N. gregoryi SP2, Natronobacterium gregoryi ATCC 43098, Natronobacterium gregoryi JCM 8860, Natronobacterium gregoryi NCIMB 2189, Natronobacterium gregoryi SP2, Natronobacterium gregoryi str. SP2, Natronobacterium gregoryi strain SP2
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