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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
htpXZn-dependent protease with chaperone function; PFAM: Peptidase family M48; Belongs to the peptidase M48B family. (294 aa)    
Predicted Functional Partners:
AFZ72690.1
Hypothetical protein.
       0.625
AFZ73271.1
Putative kinase, sugar kinase superfamily; PFAM: GHMP kinases N terminal domain.
  
    0.561
alaS
alanine--tRNA ligase/alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
  
    0.531
AFZ73356.1
Putative metal-dependent hydrolase related to alanyl-tRNA synthetase HxxxH domain protein; PFAM: Threonyl and Alanyl tRNA synthetase second additional domain; tRNA synthetases class II (A).
  
    0.496
AFZ74062.1
alanyl-tRNA synthetase; PFAM: DHHA1 domain; Threonyl and Alanyl tRNA synthetase second additional domain; tRNA synthetases class II (A).
  
    0.496
AFZ74481.1
Putative metal-dependent hydrolase related to alanyl-tRNA synthetase HxxxH domain protein; PFAM: Threonyl and Alanyl tRNA synthetase second additional domain; tRNA synthetases class II (A).
  
    0.475
AFZ72436.1
PFAM: Pyridine nucleotide-disulphide oxidoreductase; NADH:flavin oxidoreductase / NADH oxidase family.
  
  
 0.474
fumC
Fumarase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
  
  
 0.450
AFZ71960.1
PFAM: ATPase family associated with various cellular activities (AAA).
  
    0.424
AFZ72567.1
PFAM: ATPase family associated with various cellular activities (AAA).
  
    0.424
Your Current Organism:
Natronobacterium gregoryi
NCBI taxonomy Id: 797304
Other names: N. gregoryi SP2, Natronobacterium gregoryi ATCC 43098, Natronobacterium gregoryi JCM 8860, Natronobacterium gregoryi NCIMB 2189, Natronobacterium gregoryi SP2, Natronobacterium gregoryi str. SP2, Natronobacterium gregoryi strain SP2
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