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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AFZ72761.1CBS domain-containing protein; PFAM: MaoC like domain; CBS domain. (312 aa)    
Predicted Functional Partners:
AFZ72225.1
AICAR transformylase/IMP cyclohydrolase PurH; PFAM: AICARFT/IMPCHase bienzyme; Formyl transferase; TIGRFAM: phosphoribosylglycinamide formyltransferase, formyltetrahydrofolate-dependent.
  
  
 0.755
AFZ73391.1
birA, biotin-(acetyl-CoA-carboxylase) ligase; PFAM: HTH domain; Biotin protein ligase C terminal domain; Biotin/lipoate A/B protein ligase family; TIGRFAM: birA, biotin-[acetyl-CoA-carboxylase] ligase region; BirA biotin operon repressor domain.
  
  
 0.718
AFZ72463.1
PFAM: Branched-chain amino acid transport system / permease component.
  
    0.641
AFZ72478.1
3-hydroxy-3-methylglutaryl CoA synthase; PFAM: Rubredoxin-like zinc ribbon domain (DUF35_N); DUF35 OB-fold domain.
  
 
 0.637
AFZ71602.1
Flavin-dependent dehydrogenase.
  
 
 0.627
AFZ74812.1
PFAM: Citrate synthase; TIGRFAM: 2-methylcitrate synthase/citrate synthase II.
  
 
 0.603
AFZ72907.1
PFAM: lactate/malate dehydrogenase, alpha/beta C-terminal domain; lactate/malate dehydrogenase, NAD binding domain; Belongs to the LDH/MDH superfamily.
  
  
 0.597
AFZ72343.1
PFAM: Isocitrate/isopropylmalate dehydrogenase; TIGRFAM: isocitrate dehydrogenase, NADP-dependent, prokaryotic type.
  
 0.577
AFZ71681.1
acetyl-CoA acetyltransferase; PFAM: Thiolase, C-terminal domain; Thiolase, N-terminal domain.
  
 
 0.547
AFZ72064.1
acetyl-CoA acetyltransferase; PFAM: Thiolase, C-terminal domain; Thiolase, N-terminal domain.
  
 
 0.547
Your Current Organism:
Natronobacterium gregoryi
NCBI taxonomy Id: 797304
Other names: N. gregoryi SP2, Natronobacterium gregoryi ATCC 43098, Natronobacterium gregoryi JCM 8860, Natronobacterium gregoryi NCIMB 2189, Natronobacterium gregoryi SP2, Natronobacterium gregoryi str. SP2, Natronobacterium gregoryi strain SP2
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