close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AFZ72871.1PFAM: Carbonic anhydrase. (235 aa)    
Predicted Functional Partners:
AFZ74177.1
PFAM: Formate/nitrite transporter.
  
  
 0.902
AFZ73922.1
Isoleucine patch superfamily enzyme, carbonic anhydrase/acetyltransferase; PFAM: Bacterial transferase hexapeptide (three repeats).
    
 
 0.663
AFZ73984.1
Isoleucine patch superfamily enzyme, carbonic anhydrase/acetyltransferase; PFAM: Bacterial transferase hexapeptide (three repeats).
    
 
 0.663
AFZ73643.1
PRPP-binding protein, adenine/guanine phosphoribosyltransferase; PFAM: Phosphoribosyl transferase domain.
  
  
 0.632
AFZ71699.1
PFAM: Phosphoenolpyruvate carboxylase.
    
 0.613
AFZ72053.1
PRPP-binding protein, adenine/guanine phosphoribosyltransferase; May catalyze a purine salvage reaction, the substrate is unknown.
   
  
 0.581
AFZ72225.1
AICAR transformylase/IMP cyclohydrolase PurH; PFAM: AICARFT/IMPCHase bienzyme; Formyl transferase; TIGRFAM: phosphoribosylglycinamide formyltransferase, formyltetrahydrofolate-dependent.
     
 0.541
AFZ72099.1
Proton-translocating NADH-quinone oxidoreductase, chain L; PFAM: NADH-Ubiquinone/plastoquinone (complex I), various chains; NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus; TIGRFAM: proton-translocating NADH-quinone oxidoreductase, chain L.
  
  
 0.502
AFZ72672.1
Ammonia permease; PFAM: Ammonium Transporter Family; Nitrogen regulatory protein P-II; TIGRFAM: ammonium transporter; Belongs to the P(II) protein family.
     
 0.502
AFZ73452.1
Anaerobic dehydrogenase, typically selenocysteine-containing; PFAM: Molybdopterin oxidoreductase; Molydopterin dinucleotide binding domain.
 
    0.490
Your Current Organism:
Natronobacterium gregoryi
NCBI taxonomy Id: 797304
Other names: N. gregoryi SP2, Natronobacterium gregoryi ATCC 43098, Natronobacterium gregoryi JCM 8860, Natronobacterium gregoryi NCIMB 2189, Natronobacterium gregoryi SP2, Natronobacterium gregoryi str. SP2, Natronobacterium gregoryi strain SP2
Server load: high (82%) [HD]