Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
AFZ72875.1Hypothetical protein; PFAM: Cupin domain. (125 aa)    
Predicted Functional Partners:
AFZ72876.1
DNA/RNA helicase, superfamily II; PFAM: Helicase conserved C-terminal domain; DEAD/DEAH box helicase.
       0.634
AFZ74492.1
4-aminobutyrate aminotransferase family protein; PFAM: Aminotransferase class-III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
 
  
 0.625
rad25
DNA/RNA helicase, superfamily II; PFAM: Helicase conserved C-terminal domain; Type III restriction enzyme, res subunit.
 
  
 0.599
AFZ73267.1
NAD-dependent protein deacetylase, SIR2 family; PFAM: Sir2 family.
  
    0.574
AFZ72874.1
PFAM: 'Cold-shock' DNA-binding domain.
       0.509
AFZ73561.1
ABC-type molybdate transport system, periplasmic component; PFAM: Bacterial extracellular solute-binding protein.
 
    0.490
AFZ73443.1
Uncharacterized protein, gamma-carboxymuconolactone decarboxylase subunit like protein; PFAM: Carboxymuconolactone decarboxylase family; TIGRFAM: alkylhydroperoxidase AhpD family core domain.
 
   
 0.484
AFZ73521.1
glycine/D-amino acid oxidase, deaminating; PFAM: FAD dependent oxidoreductase; Rieske [2Fe-2S] domain.
  
  
 0.481
AFZ74700.1
PFAM: Spermine/spermidine synthase.
       0.455
AFZ72199.1
Hypothetical protein.
   
 
 0.449
Your Current Organism:
Natronobacterium gregoryi
NCBI taxonomy Id: 797304
Other names: N. gregoryi SP2, Natronobacterium gregoryi ATCC 43098, Natronobacterium gregoryi JCM 8860, Natronobacterium gregoryi NCIMB 2189, Natronobacterium gregoryi SP2, Natronobacterium gregoryi str. SP2, Natronobacterium gregoryi strain SP2
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