close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AFZ72960.1TIGRFAM: phosphoesterase, MJ0936 family. (222 aa)    
Predicted Functional Partners:
AFZ74638.1
Hypothetical protein.
   
 0.912
AFZ72800.1
PFAM: GTPase of unknown function; TIGRFAM: small GTP-binding protein domain.
   
 0.810
AFZ73276.1
PFAM: Protein kinase domain; FHA domain.
 
 
 0.799
rpl40e
PFAM: Ribosomal L40e family; Belongs to the eukaryotic ribosomal protein eL40 family.
   
 
 0.755
AFZ73102.1
Putative exonuclease of the beta-lactamase fold involved in RNA processing; PFAM: Metallo-beta-lactamase superfamily; RNA-metabolising metallo-beta-lactamase; Beta-Casp domain.
   
 
 0.749
ksgA
Dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
  
  
 0.718
AFZ71482.1
Putative hydrolase or acyltransferase of alpha/beta superfamily.
 
 
 0.676
AFZ71793.1
Putative hydrolase or acyltransferase of alpha/beta superfamily.
 
 
 0.675
AFZ72114.1
Putative hydrolase or acyltransferase of alpha/beta superfamily.
 
 
 0.675
AFZ72033.1
PFAM: Eukaryotic translation initiation factor 2 alpha subunit; S1 RNA binding domain.
  
 
 0.666
Your Current Organism:
Natronobacterium gregoryi
NCBI taxonomy Id: 797304
Other names: N. gregoryi SP2, Natronobacterium gregoryi ATCC 43098, Natronobacterium gregoryi JCM 8860, Natronobacterium gregoryi NCIMB 2189, Natronobacterium gregoryi SP2, Natronobacterium gregoryi str. SP2, Natronobacterium gregoryi strain SP2
Server load: low (34%) [HD]