close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AFZ73289.1PFAM: Pyroglutamyl peptidase; TIGRFAM: pyroglutamyl-peptidase I. (217 aa)    
Predicted Functional Partners:
AFZ73290.1
Metallohydrolase, glycoprotease/Kae1 family; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. The Kae1 domain likely plays a direct catalytic role in this reaction. The Bud32 domain probably displays kinase activity that regulates Kae1 function. In the N-terminal section; belongs to the KAE1 / TsaD family.
  
  
 0.718
rps27ae
PFAM: Ribosomal protein S27a; Belongs to the eukaryotic ribosomal protein eS31 family.
       0.596
rps24e
PFAM: Ribosomal protein S24e; Belongs to the eukaryotic ribosomal protein eS24 family.
       0.596
arsB
Arsenical-resistance protein; PFAM: Sodium Bile acid symporter family; TIGRFAM: arsenical-resistance protein.
 
     0.469
AFZ73581.1
Hypothetical protein; PFAM: Antibiotic biosynthesis monooxygenase; Chlorite dismutase.
       0.402
nusA
NusA family KH domain protein; Participates in transcription termination. Belongs to the NusA family.
      
 0.400
Your Current Organism:
Natronobacterium gregoryi
NCBI taxonomy Id: 797304
Other names: N. gregoryi SP2, Natronobacterium gregoryi ATCC 43098, Natronobacterium gregoryi JCM 8860, Natronobacterium gregoryi NCIMB 2189, Natronobacterium gregoryi SP2, Natronobacterium gregoryi str. SP2, Natronobacterium gregoryi strain SP2
Server load: very high (>100%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.