| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AFZ73290.1 | rpl40e | Natgr_2108 | Natgr_1147 | Metallohydrolase, glycoprotease/Kae1 family; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. The Kae1 domain likely plays a direct catalytic role in this reaction. The Bud32 domain probably displays kinase activity that regulates Kae1 function. In the N-terminal section; belongs to the KAE1 / TsaD family. | PFAM: Ribosomal L40e family; Belongs to the eukaryotic ribosomal protein eL40 family. | 0.510 |
| AFZ73290.1 | rps24e | Natgr_2108 | Natgr_2110 | Metallohydrolase, glycoprotease/Kae1 family; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. The Kae1 domain likely plays a direct catalytic role in this reaction. The Bud32 domain probably displays kinase activity that regulates Kae1 function. In the N-terminal section; belongs to the KAE1 / TsaD family. | PFAM: Ribosomal protein S24e; Belongs to the eukaryotic ribosomal protein eS24 family. | 0.955 |
| AFZ73290.1 | rps27ae | Natgr_2108 | Natgr_2109 | Metallohydrolase, glycoprotease/Kae1 family; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. The Kae1 domain likely plays a direct catalytic role in this reaction. The Bud32 domain probably displays kinase activity that regulates Kae1 function. In the N-terminal section; belongs to the KAE1 / TsaD family. | PFAM: Ribosomal protein S27a; Belongs to the eukaryotic ribosomal protein eS31 family. | 0.897 |
| AFZ73290.1 | rps6e | Natgr_2108 | Natgr_1925 | Metallohydrolase, glycoprotease/Kae1 family; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. The Kae1 domain likely plays a direct catalytic role in this reaction. The Bud32 domain probably displays kinase activity that regulates Kae1 function. In the N-terminal section; belongs to the KAE1 / TsaD family. | PFAM: Ribosomal protein S6e; Belongs to the eukaryotic ribosomal protein eS6 family. | 0.725 |
| AFZ73290.1 | spt4 | Natgr_2108 | Natgr_2316 | Metallohydrolase, glycoprotease/Kae1 family; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. The Kae1 domain likely plays a direct catalytic role in this reaction. The Bud32 domain probably displays kinase activity that regulates Kae1 function. In the N-terminal section; belongs to the KAE1 / TsaD family. | DNA-directed RNA polymerase, subunit E'; Stimulates transcription elongation; Belongs to the archaeal Spt4 family. | 0.618 |
| ef1B | rpl15e | Natgr_2101 | Natgr_2481 | Translation elongation factor aEF-1 beta; Promotes the exchange of GDP for GTP in EF-1-alpha/GDP, thus allowing the regeneration of EF-1-alpha/GTP that could then be used to form the ternary complex EF-1-alpha/GTP/AAtRNA. | Ribosomal protein L15E; PFAM: Ribosomal L15; Belongs to the eukaryotic ribosomal protein eL15 family. | 0.947 |
| ef1B | rpl37e | Natgr_2101 | Natgr_2078 | Translation elongation factor aEF-1 beta; Promotes the exchange of GDP for GTP in EF-1-alpha/GDP, thus allowing the regeneration of EF-1-alpha/GTP that could then be used to form the ternary complex EF-1-alpha/GTP/AAtRNA. | Ribosomal protein L37E; Binds to the 23S rRNA; Belongs to the eukaryotic ribosomal protein eL37 family. | 0.739 |
| ef1B | rpl40e | Natgr_2101 | Natgr_1147 | Translation elongation factor aEF-1 beta; Promotes the exchange of GDP for GTP in EF-1-alpha/GDP, thus allowing the regeneration of EF-1-alpha/GTP that could then be used to form the ternary complex EF-1-alpha/GTP/AAtRNA. | PFAM: Ribosomal L40e family; Belongs to the eukaryotic ribosomal protein eL40 family. | 0.926 |
| ef1B | rpmC | Natgr_2101 | Natgr_0308 | Translation elongation factor aEF-1 beta; Promotes the exchange of GDP for GTP in EF-1-alpha/GDP, thus allowing the regeneration of EF-1-alpha/GTP that could then be used to form the ternary complex EF-1-alpha/GTP/AAtRNA. | PFAM: Ribosomal L29 protein; TIGRFAM: ribosomal protein L29; Belongs to the universal ribosomal protein uL29 family. | 0.963 |
| ef1B | rps17E | Natgr_2101 | Natgr_3785 | Translation elongation factor aEF-1 beta; Promotes the exchange of GDP for GTP in EF-1-alpha/GDP, thus allowing the regeneration of EF-1-alpha/GTP that could then be used to form the ternary complex EF-1-alpha/GTP/AAtRNA. | Ribosomal protein S17E; PFAM: Ribosomal S17; Belongs to the eukaryotic ribosomal protein eS17 family. | 0.936 |
| ef1B | rps24e | Natgr_2101 | Natgr_2110 | Translation elongation factor aEF-1 beta; Promotes the exchange of GDP for GTP in EF-1-alpha/GDP, thus allowing the regeneration of EF-1-alpha/GTP that could then be used to form the ternary complex EF-1-alpha/GTP/AAtRNA. | PFAM: Ribosomal protein S24e; Belongs to the eukaryotic ribosomal protein eS24 family. | 0.945 |
| ef1B | rps27ae | Natgr_2101 | Natgr_2109 | Translation elongation factor aEF-1 beta; Promotes the exchange of GDP for GTP in EF-1-alpha/GDP, thus allowing the regeneration of EF-1-alpha/GTP that could then be used to form the ternary complex EF-1-alpha/GTP/AAtRNA. | PFAM: Ribosomal protein S27a; Belongs to the eukaryotic ribosomal protein eS31 family. | 0.811 |
| ef1B | rps6e | Natgr_2101 | Natgr_1925 | Translation elongation factor aEF-1 beta; Promotes the exchange of GDP for GTP in EF-1-alpha/GDP, thus allowing the regeneration of EF-1-alpha/GTP that could then be used to form the ternary complex EF-1-alpha/GTP/AAtRNA. | PFAM: Ribosomal protein S6e; Belongs to the eukaryotic ribosomal protein eS6 family. | 0.927 |
| ef1B | spt4 | Natgr_2101 | Natgr_2316 | Translation elongation factor aEF-1 beta; Promotes the exchange of GDP for GTP in EF-1-alpha/GDP, thus allowing the regeneration of EF-1-alpha/GTP that could then be used to form the ternary complex EF-1-alpha/GTP/AAtRNA. | DNA-directed RNA polymerase, subunit E'; Stimulates transcription elongation; Belongs to the archaeal Spt4 family. | 0.521 |
| rpl15e | ef1B | Natgr_2481 | Natgr_2101 | Ribosomal protein L15E; PFAM: Ribosomal L15; Belongs to the eukaryotic ribosomal protein eL15 family. | Translation elongation factor aEF-1 beta; Promotes the exchange of GDP for GTP in EF-1-alpha/GDP, thus allowing the regeneration of EF-1-alpha/GTP that could then be used to form the ternary complex EF-1-alpha/GTP/AAtRNA. | 0.947 |
| rpl15e | rpl37e | Natgr_2481 | Natgr_2078 | Ribosomal protein L15E; PFAM: Ribosomal L15; Belongs to the eukaryotic ribosomal protein eL15 family. | Ribosomal protein L37E; Binds to the 23S rRNA; Belongs to the eukaryotic ribosomal protein eL37 family. | 0.990 |
| rpl15e | rpl40e | Natgr_2481 | Natgr_1147 | Ribosomal protein L15E; PFAM: Ribosomal L15; Belongs to the eukaryotic ribosomal protein eL15 family. | PFAM: Ribosomal L40e family; Belongs to the eukaryotic ribosomal protein eL40 family. | 0.996 |
| rpl15e | rpmC | Natgr_2481 | Natgr_0308 | Ribosomal protein L15E; PFAM: Ribosomal L15; Belongs to the eukaryotic ribosomal protein eL15 family. | PFAM: Ribosomal L29 protein; TIGRFAM: ribosomal protein L29; Belongs to the universal ribosomal protein uL29 family. | 0.996 |
| rpl15e | rps17E | Natgr_2481 | Natgr_3785 | Ribosomal protein L15E; PFAM: Ribosomal L15; Belongs to the eukaryotic ribosomal protein eL15 family. | Ribosomal protein S17E; PFAM: Ribosomal S17; Belongs to the eukaryotic ribosomal protein eS17 family. | 0.996 |
| rpl15e | rps24e | Natgr_2481 | Natgr_2110 | Ribosomal protein L15E; PFAM: Ribosomal L15; Belongs to the eukaryotic ribosomal protein eL15 family. | PFAM: Ribosomal protein S24e; Belongs to the eukaryotic ribosomal protein eS24 family. | 0.996 |