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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
arsBArsenical-resistance protein; PFAM: Sodium Bile acid symporter family; TIGRFAM: arsenical-resistance protein. (392 aa)    
Predicted Functional Partners:
AFZ73938.1
Protein-tyrosine-phosphatase; PFAM: Low molecular weight phosphotyrosine protein phosphatase.
  
 0.949
AFZ73294.1
Putative transcriptional regulator; PFAM: Bacterial regulatory protein, arsR family.
  
  
 0.638
AFZ74184.1
Putative transcriptional regulator; PFAM: Bacterial regulatory protein, arsR family.
 
  
 0.511
rps27ae
PFAM: Ribosomal protein S27a; Belongs to the eukaryotic ribosomal protein eS31 family.
       0.492
rps24e
PFAM: Ribosomal protein S24e; Belongs to the eukaryotic ribosomal protein eS24 family.
       0.492
AFZ74185.1
PFAM: Predicted permease.
  
  
 0.482
AFZ73290.1
Metallohydrolase, glycoprotease/Kae1 family; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. The Kae1 domain likely plays a direct catalytic role in this reaction. The Bud32 domain probably displays kinase activity that regulates Kae1 function. In the N-terminal section; belongs to the KAE1 / TsaD family.
       0.474
AFZ73289.1
PFAM: Pyroglutamyl peptidase; TIGRFAM: pyroglutamyl-peptidase I.
 
     0.469
gap-2
Glyceraldehyde-3-phosphate dehydrogenase, type II; PFAM: Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; TIGRFAM: glyceraldehyde-3-phosphate dehydrogenase, type II.
     
 0.468
hisF
Imidazoleglycerol phosphate synthase, cyclase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
      
 0.410
Your Current Organism:
Natronobacterium gregoryi
NCBI taxonomy Id: 797304
Other names: N. gregoryi SP2, Natronobacterium gregoryi ATCC 43098, Natronobacterium gregoryi JCM 8860, Natronobacterium gregoryi NCIMB 2189, Natronobacterium gregoryi SP2, Natronobacterium gregoryi str. SP2, Natronobacterium gregoryi strain SP2
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