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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AFZ73337.1PFAM: NADH ubiquinone oxidoreductase, 20 Kd subunit; TIGRFAM: hydrogenase (NiFe) small subunit (hydA). (396 aa)    
Predicted Functional Partners:
AFZ73338.1
Ni,Fe-hydrogenase I large subunit; PFAM: Nickel-dependent hydrogenase.
 
 0.999
AFZ73340.1
PFAM: Hydrogenase maturation protease; TIGRFAM: hydrogenase maturation protease.
 
  
 0.967
AFZ74004.1
Coenzyme F420-reducing hydrogenase, alpha subunit; PFAM: Nickel-dependent hydrogenase; Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.
 
 
 0.965
AFZ73343.1
PFAM: Hydrogenase formation hypA family; TIGRFAM: hydrogenase expression/formation protein HypD.
 
  
 0.945
AFZ74368.1
2-oxoacid:acceptor oxidoreductase, alpha subunit; PFAM: domain; Pyruvate ferredoxin/flavodoxin oxidoreductase; TIGRFAM: 2-oxoacid:acceptor oxidoreductase, alpha subunit.
   
 
 0.944
AFZ74367.1
PFAM: Thiamine pyrophosphate enzyme, C-terminal TPP binding domain; TIGRFAM: 2-oxoacid:acceptor oxidoreductase, beta subunit, pyruvate/2-ketoisovalerate family.
   
 
 0.943
hypF
(NiFe) hydrogenase maturation protein HypF; PFAM: HypF finger; yrdC domain; Acylphosphatase; TIGRFAM: [NiFe] hydrogenase maturation protein HypF.
 
 
 
 0.915
hypE
Hydrogenase expression/formation protein HypE; PFAM: AIR synthase related protein, N-terminal domain; AIR synthase related protein, C-terminal domain; TIGRFAM: hydrogenase expression/formation protein HypE.
 
   
 0.911
hypB
Hydrogenase accessory protein HypB; PFAM: CobW/HypB/UreG, nucleotide-binding domain; TIGRFAM: hydrogenase accessory protein HypB.
 
  
 0.906
hypC
PFAM: HupF/HypC family; TIGRFAM: hydrogenase assembly chaperone HypC/HupF.
 
 
 0.898
Your Current Organism:
Natronobacterium gregoryi
NCBI taxonomy Id: 797304
Other names: N. gregoryi SP2, Natronobacterium gregoryi ATCC 43098, Natronobacterium gregoryi JCM 8860, Natronobacterium gregoryi NCIMB 2189, Natronobacterium gregoryi SP2, Natronobacterium gregoryi str. SP2, Natronobacterium gregoryi strain SP2
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