Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AFZ73429.1Sucrose-phosphate phosphatase-like hydrolase, Archaeal; Catalyzes the dephosphorylation of 2-phosphoglycolate. (228 aa)    
Predicted Functional Partners:
AFZ73286.1
PFAM: haloacid dehalogenase-like hydrolase; TIGRFAM: haloacid dehalogenase superfamily, subfamily IA, variant 1 with third motif having Dx(3-4)D or Dx(3-4)E.
    
  0.905
AFZ74163.1
Putative phosphatase.
    
  0.905
AFZ74327.1
Putative phosphatase; PFAM: haloacid dehalogenase-like hydrolase.
    
  0.905
AFZ72585.1
PFAM: haloacid dehalogenase-like hydrolase; TIGRFAM: haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED; haloacid dehalogenase superfamily, subfamily IA, variant 1 with third motif having Dx(3-4)D or Dx(3-4)E; Haloacid dehalogenase superfamily, subfamily IA, variant 2 with 3rd motif like haloacid dehalogenase.
 
  
 0.659
AFZ73430.1
Hypothetical protein.
       0.619
AFZ74334.1
Molybdenum-binding protein; PFAM: TOBE domain; Bacterial regulatory helix-turn-helix protein, lysR family; TIGRFAM: molybdenum-pterin binding domain; ModE molybdate transport repressor domain.
      
 0.583
pgi
PFAM: Phosphoglucose isomerase; Belongs to the GPI family.
  
 
 0.582
taw1
Wyosine biosynthesis protein TYW1; Component of the wyosine derivatives biosynthesis pathway that catalyzes the condensation of N-methylguanine with 2 carbon atoms from pyruvate to form the tricyclic 4-demethylwyosine (imG-14) on guanosine-37 of tRNA(Phe).
 
     0.565
tpiA
Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.
 
  
 0.519
AFZ73428.1
Hypothetical protein.
       0.515
Your Current Organism:
Natronobacterium gregoryi
NCBI taxonomy Id: 797304
Other names: N. gregoryi SP2, Natronobacterium gregoryi ATCC 43098, Natronobacterium gregoryi JCM 8860, Natronobacterium gregoryi NCIMB 2189, Natronobacterium gregoryi SP2, Natronobacterium gregoryi str. SP2, Natronobacterium gregoryi strain SP2
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