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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AFZ73490.1PilT domain protein; PFAM: Fcf1. (132 aa)    
Predicted Functional Partners:
AFZ72930.1
PFAM: KH domain; TIGRFAM: arCOG04150 universal archaeal KH domain protein.
  
 0.989
AFZ73491.1
PFAM: S1 RNA binding domain; RNA polymerase Rpb7-like, N-terminal domain; TIGRFAM: DNA-directed RNA polymerase (rpoE), archaeal and eukaryotic form.
 
  
 0.891
AFZ73493.1
Hypothetical protein; Catalyzes the GTP-dependent phosphorylation of the 3'- hydroxyl group of dephosphocoenzyme A to form coenzyme A (CoA).
 
     0.879
spt4
DNA-directed RNA polymerase, subunit E'; Stimulates transcription elongation; Belongs to the archaeal Spt4 family.
 
     0.875
eif2g
Translation initiation factor 2 subunit gamma; eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EIF2G subfamily.
  
    0.811
AFZ71452.1
rRNA biogenesis protein; PFAM: Putative snoRNA binding domain; BAAT / Acyl-CoA thioester hydrolase C terminal.
  
 
 0.734
AFZ73210.1
Putative GTPase; PFAM: Nucleolar GTP-binding protein 1 (NOG1); TIGRFAM: small GTP-binding protein domain.
 
 
 0.708
AFZ73648.1
RIO-like serine/threonine protein kinase fused to N-terminal HTH domain protein; PFAM: RIO1 family; Rio2, N-terminal.
  
  
 0.699
rtcA
RNA 3'-phosphate cyclase; Catalyzes the conversion of 3'-phosphate to a 2',3'-cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps: (A) adenylation of the enzyme by ATP; (B) transfer of adenylate to an RNA-N3'P to produce RNA-N3'PP5'A; (C) and attack of the adjacent 2'-hydroxyl on the 3'-phosphorus in the diester linkage to produce the cyclic end product. The biological role of this enzyme is unknown but it is likely to function in some aspects of cellular RNA processing.
  
  
 0.690
rps24e
PFAM: Ribosomal protein S24e; Belongs to the eukaryotic ribosomal protein eS24 family.
 
    0.685
Your Current Organism:
Natronobacterium gregoryi
NCBI taxonomy Id: 797304
Other names: N. gregoryi SP2, Natronobacterium gregoryi ATCC 43098, Natronobacterium gregoryi JCM 8860, Natronobacterium gregoryi NCIMB 2189, Natronobacterium gregoryi SP2, Natronobacterium gregoryi str. SP2, Natronobacterium gregoryi strain SP2
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