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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AFZ73621.1K+ transport system, NAD-binding component; PFAM: TrkA-N domain; TrkA-C domain. (222 aa)    
Predicted Functional Partners:
AFZ71454.1
Trk-type K+ transport system, membrane component; PFAM: Cation transport protein.
 
 
 0.873
AFZ71459.1
Trk-type K+ transport system, membrane component; PFAM: Cation transport protein.
 
 
 0.873
AFZ73588.1
Molybdopterin converting factor, large subunit; PFAM: MoaE protein.
   
    0.580
hemD
PFAM: Uroporphyrinogen-III synthase HemD.
  
    0.566
AFZ73622.1
PFAM: Permease family.
       0.560
AFZ71679.1
P-type ATPase, translocating; PFAM: E1-E2 ATPase; Cation transporting ATPase, C-terminus; Cation transporter/ATPase, N-terminus; haloacid dehalogenase-like hydrolase; TIGRFAM: plasma-membrane calcium-translocating P-type ATPase; ATPase, P-type (transporting), HAD superfamily, subfamily IC.
 
  
 0.523
AFZ74730.1
PFAM: NOL1/NOP2/sun family; TIGRFAM: NOL1/NOP2/sun family putative RNA methylase; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
  
    0.444
trkA
K+ transport system, NAD-binding component; PFAM: TrkA-N domain; TrkA-C domain.
 
   
0.425
AFZ73623.1
Glutathione S-transferase; PFAM: Glutaredoxin.
       0.408
nadK
Inositol monophosphatase/fructose-1,6-bisphosphatase family protein; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
  
    0.406
Your Current Organism:
Natronobacterium gregoryi
NCBI taxonomy Id: 797304
Other names: N. gregoryi SP2, Natronobacterium gregoryi ATCC 43098, Natronobacterium gregoryi JCM 8860, Natronobacterium gregoryi NCIMB 2189, Natronobacterium gregoryi SP2, Natronobacterium gregoryi str. SP2, Natronobacterium gregoryi strain SP2
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