close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AFZ73663.1Methylase involved in ubiquinone/menaquinone biosynthesis; PFAM: Methyltransferase domain. (249 aa)    
Predicted Functional Partners:
AFZ72001.1
NADH:ubiquinone oxidoreductase 49 kD subunit 7; PFAM: Respiratory-chain NADH dehydrogenase, 30 Kd subunit; Respiratory-chain NADH dehydrogenase, 49 Kd subunit.
   
 0.834
AFZ72105.1
NADH:ubiquinone oxidoreductase 49 kD subunit 7; PFAM: Respiratory-chain NADH dehydrogenase, 30 Kd subunit; Respiratory-chain NADH dehydrogenase, 49 Kd subunit.
   
 0.834
rps5p
Ribosomal protein S5/S2; With S4 and S12 plays an important role in translational accuracy.
  
 
 0.654
AFZ72808.1
Methylase involved in ubiquinone/menaquinone biosynthesis; PFAM: Methyltransferase domain.
  
   
 0.618
rps24e
PFAM: Ribosomal protein S24e; Belongs to the eukaryotic ribosomal protein eS24 family.
  
 
  0.559
AFZ71696.1
Methylase involved in ubiquinone/menaquinone biosynthesis; PFAM: Methyltransferase domain.
  
   
 0.558
AFZ71320.1
Phytoene/squalene synthetase; PFAM: Squalene/phytoene synthase.
  
 
 0.553
rps19e
Ribosomal protein S19E (S16A); May be involved in maturation of the 30S ribosomal subunit. Belongs to the eukaryotic ribosomal protein eS19 family.
  
  0.549
AFZ73662.1
Hypothetical protein.
       0.534
flpA
Fibrillarin-like rRNA methylase; Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA; Belongs to the methyltransferase superfamily. Fibrillarin family.
  
 0.528
Your Current Organism:
Natronobacterium gregoryi
NCBI taxonomy Id: 797304
Other names: N. gregoryi SP2, Natronobacterium gregoryi ATCC 43098, Natronobacterium gregoryi JCM 8860, Natronobacterium gregoryi NCIMB 2189, Natronobacterium gregoryi SP2, Natronobacterium gregoryi str. SP2, Natronobacterium gregoryi strain SP2
Server load: low (40%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.