STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
tmcAPutative P-loop ATPase fused to an acetyltransferase; Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP). (763 aa)    
Predicted Functional Partners:
AFZ71452.1
rRNA biogenesis protein; PFAM: Putative snoRNA binding domain; BAAT / Acyl-CoA thioester hydrolase C terminal.
  
 
 0.989
AFZ72930.1
PFAM: KH domain; TIGRFAM: arCOG04150 universal archaeal KH domain protein.
   
 
 0.960
rpl7ae
50S ribosomal protein L7Ae; Multifunctional RNA-binding protein that recognizes the K- turn motif in ribosomal RNA, the RNA component of RNase P, box H/ACA, box C/D and box C'/D' sRNAs.
 
 
 0.951
rtcA
RNA 3'-phosphate cyclase; Catalyzes the conversion of 3'-phosphate to a 2',3'-cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps: (A) adenylation of the enzyme by ATP; (B) transfer of adenylate to an RNA-N3'P to produce RNA-N3'PP5'A; (C) and attack of the adjacent 2'-hydroxyl on the 3'-phosphorus in the diester linkage to produce the cyclic end product. The biological role of this enzyme is unknown but it is likely to function in some aspects of cellular RNA processing.
   
 
 0.943
rps28e
PFAM: Ribosomal protein S28e; Belongs to the eukaryotic ribosomal protein eS28 family.
   
   0.915
rps3ae
PFAM: Ribosomal S3Ae family; Belongs to the eukaryotic ribosomal protein eS1 family.
  
   0.890
truB
rRNA pseudouridine synthase, putative; Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 2 subfamily.
  
 
 0.886
AFZ73210.1
Putative GTPase; PFAM: Nucleolar GTP-binding protein 1 (NOG1); TIGRFAM: small GTP-binding protein domain.
  
   0.882
rps15p
Ribosomal protein S15P/S13E; PFAM: Ribosomal S13/S15 N-terminal domain; Ribosomal protein S15.
  
 
 0.875
rps6e
PFAM: Ribosomal protein S6e; Belongs to the eukaryotic ribosomal protein eS6 family.
  
   0.871
Your Current Organism:
Natronobacterium gregoryi
NCBI taxonomy Id: 797304
Other names: N. gregoryi SP2, Natronobacterium gregoryi ATCC 43098, Natronobacterium gregoryi JCM 8860, Natronobacterium gregoryi NCIMB 2189, Natronobacterium gregoryi SP2, Natronobacterium gregoryi str. SP2, Natronobacterium gregoryi strain SP2
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