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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AFZ73752.1Site-specific recombinase, DNA invertase Pin; PFAM: Resolvase, N terminal domain. (237 aa)    
Predicted Functional Partners:
AFZ73751.1
Hypothetical protein.
       0.773
fen
Flap structure-specific endonuclease; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double-stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair [...]
      
 0.646
AFZ74512.1
RecA-superfamily ATPase possibly involved in signal transduction; PFAM: KaiC.
      
 0.604
AFZ72174.1
Hypothetical protein.
   
    0.576
AFZ73654.1
Kef-type K+ transport system, membrane component; PFAM: TrkA-N domain; Sodium/hydrogen exchanger family.
   
    0.514
AFZ73655.1
Kef-type K+ transport system, membrane component; PFAM: TrkA-N domain; Sodium/hydrogen exchanger family.
   
    0.514
AFZ74089.1
Kef-type K+ transport system, membrane component; PFAM: TrkA-N domain; Sodium/hydrogen exchanger family.
   
    0.514
AFZ74090.1
Kef-type K+ transport system, membrane component; PFAM: TrkA-N domain; Sodium/hydrogen exchanger family.
   
    0.514
AFZ74092.1
Kef-type K+ transport system, predicted NAD-binding component; PFAM: TrkA-N domain; Sodium/hydrogen exchanger family.
   
    0.514
AFZ74093.1
Kef-type K+ transport system, membrane component; PFAM: TrkA-N domain; Sodium/hydrogen exchanger family.
   
    0.514
Your Current Organism:
Natronobacterium gregoryi
NCBI taxonomy Id: 797304
Other names: N. gregoryi SP2, Natronobacterium gregoryi ATCC 43098, Natronobacterium gregoryi JCM 8860, Natronobacterium gregoryi NCIMB 2189, Natronobacterium gregoryi SP2, Natronobacterium gregoryi str. SP2, Natronobacterium gregoryi strain SP2
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