STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AFZ73876.1Sugar kinase, ribokinase; PFAM: pfkB family carbohydrate kinase. (319 aa)    
Predicted Functional Partners:
AFZ73647.1
PFAM: KDPG and KHG aldolase; TIGRFAM: Entner-Doudoroff aldolase.
  
  
  0.972
AFZ71339.1
Enolase superfamily enzyme related to L-alanine-DL-glutamate epimerase; PFAM: Mandelate racemase / muconate lactonizing enzyme, C-terminal domain; Mandelate racemase / muconate lactonizing enzyme, N-terminal domain.
 
  
 0.936
AFZ73357.1
Enolase superfamily enzyme related to L-alanine-DL-glutamate epimerase; PFAM: Mandelate racemase / muconate lactonizing enzyme, C-terminal domain; Mandelate racemase / muconate lactonizing enzyme, N-terminal domain.
 
  
 0.936
AFZ72225.1
AICAR transformylase/IMP cyclohydrolase PurH; PFAM: AICARFT/IMPCHase bienzyme; Formyl transferase; TIGRFAM: phosphoribosylglycinamide formyltransferase, formyltetrahydrofolate-dependent.
  
 
 0.743
hisA
PFAM: Histidine biosynthesis protein; TIGRFAM: phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase.
  
  
 0.737
AFZ73318.1
Sugar phosphate isomerase/epimerase; PFAM: AP endonuclease family 2 C terminus; Xylose isomerase-like TIM barrel.
 
  
 0.682
AFZ71887.1
Sugar phosphate isomerase/epimerase; PFAM: Xylose isomerase-like TIM barrel.
  
  
 0.629
AFZ74059.1
PFAM: Glycine cleavage T-protein C-terminal barrel domain; Aminomethyltransferase folate-binding domain; FAD dependent oxidoreductase.
  
  
 0.610
ribH
6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.
  
  
 0.600
AFZ73877.1
PFAM: Acetyltransferase (GNAT) family.
     
 0.575
Your Current Organism:
Natronobacterium gregoryi
NCBI taxonomy Id: 797304
Other names: N. gregoryi SP2, Natronobacterium gregoryi ATCC 43098, Natronobacterium gregoryi JCM 8860, Natronobacterium gregoryi NCIMB 2189, Natronobacterium gregoryi SP2, Natronobacterium gregoryi str. SP2, Natronobacterium gregoryi strain SP2
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