close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AFZ73967.1PFAM: Protein of unknown function (DUF444). (442 aa)    
Predicted Functional Partners:
AFZ73968.1
PFAM: SpoVR like protein.
 
  
 0.996
AFZ73965.1
PFAM: PrkA AAA domain; PrkA serine protein kinase C-terminal domain.
 
  
 0.993
AFZ73966.1
PFAM: PrkA AAA domain; PrkA serine protein kinase C-terminal domain.
 
  
 0.993
AFZ73823.1
Phosphate uptake regulator; PFAM: PhoU domain; SpoVT / AbrB like domain.
  
    0.470
AFZ73969.1
PFAM: HEAT repeat.
       0.461
AFZ71408.1
PFAM: Integral membrane protein DUF106.
  
    0.430
otsB
Trehalose-phosphatase; Removes the phosphate from trehalose 6-phosphate to produce free trehalose.
  
    0.427
Your Current Organism:
Natronobacterium gregoryi
NCBI taxonomy Id: 797304
Other names: N. gregoryi SP2, Natronobacterium gregoryi ATCC 43098, Natronobacterium gregoryi JCM 8860, Natronobacterium gregoryi NCIMB 2189, Natronobacterium gregoryi SP2, Natronobacterium gregoryi str. SP2, Natronobacterium gregoryi strain SP2
Server load: low (38%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.