STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AFZ73973.1PFAM: Response regulator receiver domain. (148 aa)    
Predicted Functional Partners:
AFZ74345.1
PAS domain S-box; PFAM: GAF domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; PAS fold; TIGRFAM: PAS domain S-box.
 
   
 0.874
AFZ71810.1
PAS domain S-box; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; GAF domain; His Kinase A (phosphoacceptor) domain; PAS fold; TIGRFAM: PAS domain S-box.
 
   
 0.872
AFZ74365.1
PAS domain S-box; PFAM: PAS fold; TIGRFAM: PAS domain S-box.
 
   
 0.746
AFZ73974.1
Dehydrogenase of unknown specificity, short-chain alcohol dehydrogenase like protein; PFAM: short chain dehydrogenase.
   
   0.671
AFZ72280.1
PFAM: HTH DNA binding domain; GAF domain; Response regulator receiver domain.
 
   
 0.667
AFZ71769.1
PFAM: CheB methylesterase; Response regulator receiver domain.
 
 
 0.630
cheB
Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family.
 
 
 0.616
AFZ71771.1
Chemotaxis signal transduction protein; PFAM: CheW-like domain.
 
 
 0.615
AFZ73141.1
Chemotaxis signal transduction protein; PFAM: CheW-like domain.
  
 
 0.615
AFZ72185.1
PAS domain S-box; PFAM: HTH DNA binding domain; GAF domain; PAS fold; TIGRFAM: PAS domain S-box.
 
 
 
 0.603
Your Current Organism:
Natronobacterium gregoryi
NCBI taxonomy Id: 797304
Other names: N. gregoryi SP2, Natronobacterium gregoryi ATCC 43098, Natronobacterium gregoryi JCM 8860, Natronobacterium gregoryi NCIMB 2189, Natronobacterium gregoryi SP2, Natronobacterium gregoryi str. SP2, Natronobacterium gregoryi strain SP2
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