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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mchMethenyltetrahydromethanopterin cyclohydrolase; Catalyzes the hydrolysis of methenyl-H(4)MPT(+) to 5-formyl- H(4)MPT. (310 aa)    
Predicted Functional Partners:
AFZ71658.1
beta-RFAP synthase; Catalyzes the condensation of 4-aminobenzoate (pABA) with 5- phospho-alpha-D-ribose 1-diphosphate (PRPP) to produce beta- ribofuranosylaminobenzene 5'-phosphate (beta-RFA-P).
 
     0.814
AFZ74883.1
Triphosphoribosyl-dephospho-CoA synthetase; PFAM: ATP:dephospho-CoA triphosphoribosyl transferase.
 
     0.806
AFZ73994.1
Putative HD superfamily hydrolase; PFAM: HD domain.
       0.773
AFZ74360.1
PFAM: CoA binding domain; ATP-grasp domain; TIGRFAM: acetyl coenzyme A synthetase (ADP forming), alpha domain.
      
 0.705
AFZ73996.1
Copper chaperone; PFAM: Heavy-metal-associated domain.
       0.612
mer
Flavin-dependent oxidoreductase, F420-dependent methylene-tetrahydromethanopterin reductase; Catalyzes the oxidation of methyl-H(4)MPT to methylene- H(4)MPT.
  
   
 0.578
AFZ73997.1
PFAM: Domain of unknown function DUF77; TIGRFAM: uncharacterized protein, MTH1187 family.
       0.537
AFZ71613.1
PFAM: Malic enzyme, NAD binding domain; Phosphate acetyl/butaryl transferase; Malic enzyme, N-terminal domain; TIGRFAM: phosphate acetyltransferase.
      
 0.520
AFZ72608.1
Fe-S oxidoreductase; PFAM: Cysteine-rich domain.
      
 0.514
AFZ71858.1
PFAM: 6-pyruvoyl tetrahydropterin synthase.
 
     0.479
Your Current Organism:
Natronobacterium gregoryi
NCBI taxonomy Id: 797304
Other names: N. gregoryi SP2, Natronobacterium gregoryi ATCC 43098, Natronobacterium gregoryi JCM 8860, Natronobacterium gregoryi NCIMB 2189, Natronobacterium gregoryi SP2, Natronobacterium gregoryi str. SP2, Natronobacterium gregoryi strain SP2
Server load: low (28%) [HD]
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