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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AFZ74105.1Putative dehydrogenase; PFAM: Oxidoreductase family, C-terminal alpha/beta domain; Oxidoreductase family, NAD-binding Rossmann fold. (368 aa)    
Predicted Functional Partners:
AFZ74107.1
PFAM: NAD dependent epimerase/dehydratase family.
  
  
 0.797
AFZ74106.1
Hypothetical protein; PFAM: Domain of unknown function (DUF362).
       0.786
AFZ74112.1
Putative PLP-dependent enzyme possibly involved in cell wall biogenesis; PFAM: DegT/DnrJ/EryC1/StrS aminotransferase family; Belongs to the DegT/DnrJ/EryC1 family.
 
  
 0.759
AFZ71584.1
Putative dehydrogenase; PFAM: Oxidoreductase family, NAD-binding Rossmann fold.
  
     0.738
AFZ73318.1
Sugar phosphate isomerase/epimerase; PFAM: AP endonuclease family 2 C terminus; Xylose isomerase-like TIM barrel.
 
  
 0.728
AFZ74108.1
PFAM: Protein of unknown function (DUF354).
 
     0.633
AFZ71887.1
Sugar phosphate isomerase/epimerase; PFAM: Xylose isomerase-like TIM barrel.
  
  
 0.609
lysS
lysyl-tRNA synthetase (class II); PFAM: tRNA synthetases class II (D, K and N); OB-fold nucleic acid binding domain; TIGRFAM: lysyl-tRNA synthetase, eukaryotic and non-spirochete bacterial; Belongs to the class-II aminoacyl-tRNA synthetase family.
  
    0.574
AFZ71531.1
PFAM: UDP-N-acetylglucosamine 2-epimerase; TIGRFAM: UDP-N-acetylglucosamine 2-epimerase.
  
  
 0.563
AFZ72362.1
Sugar kinase, ribokinase; PFAM: pfkB family carbohydrate kinase; Belongs to the carbohydrate kinase PfkB family.
 
  
 0.520
Your Current Organism:
Natronobacterium gregoryi
NCBI taxonomy Id: 797304
Other names: N. gregoryi SP2, Natronobacterium gregoryi ATCC 43098, Natronobacterium gregoryi JCM 8860, Natronobacterium gregoryi NCIMB 2189, Natronobacterium gregoryi SP2, Natronobacterium gregoryi str. SP2, Natronobacterium gregoryi strain SP2
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.