Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
gvpAGas vesicle protein; Gas vesicles are small, hollow, gas filled protein structures that are found in several microbial planktonic microorganisms. They allow the positioning of the organism at the favorable depth for growth. GvpA type proteins form the essential core of the structure. (95 aa)    
Predicted Functional Partners:
gvpN
Gas vesicle protein GvpN; PFAM: AAA domain (dynein-related subfamily); TIGRFAM: gas vesicle protein GvpN.
 
   
 0.998
AFZ74215.1
PFAM: Gas vesicle synthesis protein GvpO.
 
   
 0.992
AFZ74206.1
PFAM: Gas vesicle synthesis protein GvpL/GvpF.
 
   
 0.922
AFZ74212.1
PFAM: Gas vesicle synthesis protein GvpL/GvpF.
 
   
 0.911
AFZ74207.1
PFAM: Gas vesicle protein K.
 
   
 0.910
AFZ74208.1
Gas vesicle protein; Gas vesicles are small, hollow, gas filled protein structures that are found in several microbial planktonic microorganisms. They allow the positioning of the organism at the favorable depth for growth.
 
   
 0.908
tfb-4
Transcription initiation factor TFIIIB, Brf1 subunit/transcription initiation factor TFIIB; Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB).
      
 0.757
tfb-6
Transcription initiation factor TFIIIB, Brf1 subunit/transcription initiation factor TFIIB; Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB).
      
 0.757
tfb-5
Transcription initiation factor TFIIIB, Brf1 subunit/transcription initiation factor TFIIB; Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB).
      
 0.747
ppa
Inorganic pyrophosphatase; Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
      
 0.723
Your Current Organism:
Natronobacterium gregoryi
NCBI taxonomy Id: 797304
Other names: N. gregoryi SP2, Natronobacterium gregoryi ATCC 43098, Natronobacterium gregoryi JCM 8860, Natronobacterium gregoryi NCIMB 2189, Natronobacterium gregoryi SP2, Natronobacterium gregoryi str. SP2, Natronobacterium gregoryi strain SP2
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