STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AFZ74294.1PFAM: NIF3 (NGG1p interacting factor 3); TIGRFAM: dinuclear metal center protein, YbgI/SA1388 family. (255 aa)    
Predicted Functional Partners:
AFZ74295.1
PFAM: Acetamidase/Formamidase family.
       0.552
folP-2
Dihydropteroate synthase; PFAM: Pterin binding enzyme; Mur ligase family, glutamate ligase domain; Mur ligase middle domain; TIGRFAM: dihydropteroate synthase; folylpolyglutamate synthase/dihydrofolate synthase.
 
     0.484
AFZ73910.1
PFAM: Aminotransferase class I and II; TIGRFAM: L-threonine-O-3-phosphate decarboxylase.
  
  
 0.475
hisC
PFAM: Aminotransferase class I and II; TIGRFAM: histidinol-phosphate aminotransferase.
  
  
 0.475
AFZ74822.1
PFAM: PHP domain; TIGRFAM: histidinol phosphate phosphatase, HisJ family.
 
    0.468
flpA
Fibrillarin-like rRNA methylase; Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA; Belongs to the methyltransferase superfamily. Fibrillarin family.
  
 
 0.454
AFZ74293.1
PFAM: HAMP domain; Methyl-accepting chemotaxis protein (MCP) signaling domain.
       0.452
AFZ74159.1
PFAM: Protein of unknown function DUF88; TIGRFAM: TIGR00288 family protein.
 
   
 0.440
AFZ72199.1
Hypothetical protein.
     
 0.437
AFZ73669.1
PFAM: PP-loop family; TIGRFAM: TIGR00269 family protein.
  
  
 0.434
Your Current Organism:
Natronobacterium gregoryi
NCBI taxonomy Id: 797304
Other names: N. gregoryi SP2, Natronobacterium gregoryi ATCC 43098, Natronobacterium gregoryi JCM 8860, Natronobacterium gregoryi NCIMB 2189, Natronobacterium gregoryi SP2, Natronobacterium gregoryi str. SP2, Natronobacterium gregoryi strain SP2
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.