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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hemAglutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). (443 aa)    
Predicted Functional Partners:
hemL
PFAM: Aminotransferase class-III; TIGRFAM: glutamate-1-semialdehyde-2,1-aminomutase.
 
 0.992
hemC
PFAM: Porphobilinogen deaminase, C-terminal domain; Porphobilinogen deaminase, dipyromethane cofactor binding domain; TIGRFAM: porphobilinogen deaminase.
  
 0.979
gltX
glutamyl-tRNA synthetase, archaeal and eukaryotic family; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
  
  
 0.928
AFZ72673.1
PFAM: Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family.
 
  
 0.870
hemD
PFAM: Uroporphyrinogen-III synthase HemD.
 
  
 0.845
AFZ71367.1
uroporphyrin-III C-methyltransferase; PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases; TIGRFAM: uroporphyrin-III C-methyltransferase; Belongs to the precorrin methyltransferase family.
 
  
 0.808
AFZ71380.1
PFAM: Magnesium chelatase, subunit ChlI; von Willebrand factor type A domain.
  
  
 0.780
hemE
Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
 
  
 0.749
AFZ71402.1
Heme/copper-type cytochrome/quinol oxidase, subunit 1; PFAM: Cytochrome c oxidase subunit III; Cytochrome C and Quinol oxidase polypeptide I; Belongs to the heme-copper respiratory oxidase family.
     
 0.721
AFZ74267.1
ABC-type transport system involved in cytochrome c biogenesis, permease component; PFAM: Cytochrome C assembly protein.
  
  
 0.699
Your Current Organism:
Natronobacterium gregoryi
NCBI taxonomy Id: 797304
Other names: N. gregoryi SP2, Natronobacterium gregoryi ATCC 43098, Natronobacterium gregoryi JCM 8860, Natronobacterium gregoryi NCIMB 2189, Natronobacterium gregoryi SP2, Natronobacterium gregoryi str. SP2, Natronobacterium gregoryi strain SP2
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