close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AFZ74327.1Putative phosphatase; PFAM: haloacid dehalogenase-like hydrolase. (212 aa)    
Predicted Functional Partners:
AFZ73628.1
Phosphoglycerate dehydrogenase-like oxidoreductase; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain; D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain.
 
  
 0.921
AFZ73286.1
PFAM: haloacid dehalogenase-like hydrolase; TIGRFAM: haloacid dehalogenase superfamily, subfamily IA, variant 1 with third motif having Dx(3-4)D or Dx(3-4)E.
  
  
 
0.912
AFZ74163.1
Putative phosphatase.
  
  
  0.912
AFZ73429.1
Sucrose-phosphate phosphatase-like hydrolase, Archaeal; Catalyzes the dephosphorylation of 2-phosphoglycolate.
    
 0.906
phhB
PFAM: Pterin 4 alpha carbinolamine dehydratase.
  
  
 0.750
AFZ72413.1
DNA/RNA helicase, superfamily I; PFAM: UvrD/REP helicase.
 
 
 
 0.646
AFZ71488.1
Methyltransferase family protein; PFAM: Methyltransferase domain.
  
     0.616
AFZ72704.1
DNA helicase, Rad3; PFAM: DEAD_2.
 
   
 0.607
AFZ73096.1
Putative DHD superfamily phosphohydrolase.
  
     0.603
AFZ74816.1
Hypothetical protein.
  
     0.603
Your Current Organism:
Natronobacterium gregoryi
NCBI taxonomy Id: 797304
Other names: N. gregoryi SP2, Natronobacterium gregoryi ATCC 43098, Natronobacterium gregoryi JCM 8860, Natronobacterium gregoryi NCIMB 2189, Natronobacterium gregoryi SP2, Natronobacterium gregoryi str. SP2, Natronobacterium gregoryi strain SP2
Server load: low (32%) [HD]