Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AFZ74362.1Hypothetical protein; PFAM: PRC-barrel domain. (100 aa)    
Predicted Functional Partners:
AFZ74810.1
PFAM: Protein of unknown function (DUF552).
  
  
 0.816
AFZ72242.1
Hypothetical protein; PFAM: PRC-barrel domain.
  
   
 0.760
AFZ72779.1
PFAM: Peptidase S24-like.
  
     0.750
AFZ74914.1
PFAM: Protein of unknown function (DUF1119).
  
     0.750
AFZ72521.1
Single-stranded DNA-binding protein.
  
     0.742
AFZ72522.1
Hypothetical protein.
  
     0.733
AFZ72798.1
PFAM: Peptidase S24-like.
  
     0.732
AFZ72092.1
Hypothetical protein; Manually curated.
  
     0.731
AFZ74834.1
PFAM: Uncharacterized protein conserved in archaea (DUF2240).
  
     0.726
AFZ71853.1
Hypothetical protein.
  
     0.712
Your Current Organism:
Natronobacterium gregoryi
NCBI taxonomy Id: 797304
Other names: N. gregoryi SP2, Natronobacterium gregoryi ATCC 43098, Natronobacterium gregoryi JCM 8860, Natronobacterium gregoryi NCIMB 2189, Natronobacterium gregoryi SP2, Natronobacterium gregoryi str. SP2, Natronobacterium gregoryi strain SP2
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