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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AFZ74363.1Exopolyphosphatase-like enzyme; PFAM: DHH family; TrkA-N domain. (482 aa)    
Predicted Functional Partners:
AFZ74142.1
PFAM: ScpA/B protein.
 
    0.638
dacZ
Hypothetical protein; Diadenylate cyclase that catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c-di-AMP is a second messenger for intracellular signal transduction involved in the control of important regulatory processes such as osmoregulation.
 
   
 0.559
AFZ71638.1
PFAM: Protein of unknown function (DUF555); Belongs to the UPF0212 family.
  
     0.550
AFZ74733.1
PFAM: Protein of unknown function (DUF555); Belongs to the UPF0212 family.
  
     0.550
AFZ71599.1
Putative acyltransferase; PFAM: Bacterial transferase hexapeptide (three repeats); Protein of unknown function, DUF583.
  
     0.502
infB
Translation initiation factor aIF-2/yIF-2; Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2.
  
  
 0.480
AFZ72954.1
PFAM: Protein of unknown function (DUF460).
  
     0.453
AFZ71884.1
PFAM: Protein of unknown function (DUF1628); TIGRFAM: archaeal flagellin N-terminal-like domain.
  
     0.449
cofC
2-phospho-L-lactate guanylyltransferase; Guanylyltransferase that catalyzes the activation of phosphoenolpyruvate (PEP) as enolpyruvoyl-2-diphospho-5'-guanosine, via the condensation of PEP with GTP. It is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor; Belongs to the CofC family.
  
     0.446
AFZ72801.1
PFAM: Uncharacterized protein conserved in archaea (DUF2073).
  
     0.442
Your Current Organism:
Natronobacterium gregoryi
NCBI taxonomy Id: 797304
Other names: N. gregoryi SP2, Natronobacterium gregoryi ATCC 43098, Natronobacterium gregoryi JCM 8860, Natronobacterium gregoryi NCIMB 2189, Natronobacterium gregoryi SP2, Natronobacterium gregoryi str. SP2, Natronobacterium gregoryi strain SP2
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