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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AFZ74443.1PFAM: HTH DNA binding domain. (239 aa)    
Predicted Functional Partners:
AFZ74442.1
Mn2+-dependent serine/threonine protein kinase; PFAM: RIO1 family.
 
     0.823
AFZ72976.1
Hypothetical protein.
  
     0.691
AFZ74069.1
Methyltransferase family protein; PFAM: Methyltransferase domain.
  
     0.595
AFZ72549.1
Hypothetical protein.
  
     0.584
AFZ73905.1
Putative HAD superfamily hydrolase; PFAM: haloacid dehalogenase-like hydrolase.
  
     0.579
AFZ73401.1
Transposase; PFAM: Putative transposase DNA-binding domain; Probable transposase.
  
   
 0.531
AFZ72682.1
Chemotaxis protein CheC, inhibitor of MCP methylation; PFAM: CheC-like family.
  
     0.530
AFZ73762.1
Site-specific recombinase XerD; PFAM: Phage integrase family.
  
     0.525
AFZ74453.1
PFAM: Domain of unknown function DUF87.
  
     0.517
AFZ73823.1
Phosphate uptake regulator; PFAM: PhoU domain; SpoVT / AbrB like domain.
  
     0.516
Your Current Organism:
Natronobacterium gregoryi
NCBI taxonomy Id: 797304
Other names: N. gregoryi SP2, Natronobacterium gregoryi ATCC 43098, Natronobacterium gregoryi JCM 8860, Natronobacterium gregoryi NCIMB 2189, Natronobacterium gregoryi SP2, Natronobacterium gregoryi str. SP2, Natronobacterium gregoryi strain SP2
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.