close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AFZ74453.1PFAM: Domain of unknown function DUF87. (571 aa)    
Predicted Functional Partners:
AFZ72549.1
Hypothetical protein.
  
     0.639
AFZ73843.1
Putative ATPase.
  
     0.605
AFZ73776.1
NurA domain-containing protein; PFAM: NurA domain.
   
 
 0.561
AFZ72300.1
PFAM: HTH DNA binding domain.
  
     0.530
AFZ71757.1
Archaeal flagella assembly protein J; PFAM: Bacterial type II secretion system protein F domain.
 
   
 0.517
AFZ74443.1
PFAM: HTH DNA binding domain.
  
     0.517
AFZ74454.1
Hypothetical protein; PFAM: Type I phosphodiesterase / nucleotide pyrophosphatase.
       0.503
AFZ74455.1
Hypothetical protein.
       0.503
AFZ72093.1
Hypothetical protein.
  
     0.499
AFZ73426.1
TIGRFAM: PGF-CTERM archaeal protein-sorting signal.
  
     0.493
Your Current Organism:
Natronobacterium gregoryi
NCBI taxonomy Id: 797304
Other names: N. gregoryi SP2, Natronobacterium gregoryi ATCC 43098, Natronobacterium gregoryi JCM 8860, Natronobacterium gregoryi NCIMB 2189, Natronobacterium gregoryi SP2, Natronobacterium gregoryi str. SP2, Natronobacterium gregoryi strain SP2
Server load: low (22%) [HD]