close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AFZ74689.1Cystathionine beta-lyase/cystathionine gamma-synthase; PFAM: Cys/Met metabolism PLP-dependent enzyme. (411 aa)    
Predicted Functional Partners:
AFZ71877.1
Cysteine synthase; PFAM: Pyridoxal-phosphate dependent enzyme.
 
 0.976
cysK
Cysteine synthase A; PFAM: Pyridoxal-phosphate dependent enzyme; TIGRFAM: cysteine synthase A; cysteine synthases.
  
 0.973
AFZ74475.1
Cysteine synthase; PFAM: Pyridoxal-phosphate dependent enzyme.
  
 0.972
metE
Methionine synthase II (cobalamin-independent); Catalyzes the transfer of a methyl group to L-homocysteine resulting in methionine formation. The physiological methyl donor is unknown.
  
 
 0.959
AFZ73320.1
Methionine synthase II (cobalamin-independent); PFAM: Cobalamin-independent synthase, N-terminal domain.
  
 
 0.959
AFZ74290.1
Rhodanese-related sulfurtransferase; PFAM: Rhodanese-like domain.
 
 
 0.932
AFZ72111.1
PFAM: Aminotransferase class I and II.
  
 
 0.930
AFZ74078.1
PFAM: Aminotransferase class I and II.
  
 
 0.930
AFZ72157.1
PFAM: Aminotransferase class IV; TIGRFAM: branched-chain amino acid aminotransferase, group I; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.
   
 0.929
ilvE
Branched-chain amino acid aminotransferase, group I; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.
   
 0.929
Your Current Organism:
Natronobacterium gregoryi
NCBI taxonomy Id: 797304
Other names: N. gregoryi SP2, Natronobacterium gregoryi ATCC 43098, Natronobacterium gregoryi JCM 8860, Natronobacterium gregoryi NCIMB 2189, Natronobacterium gregoryi SP2, Natronobacterium gregoryi str. SP2, Natronobacterium gregoryi strain SP2
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.