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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AFZ74926.1Transcriptional regulator; PFAM: IclR helix-turn-helix domain; AsnC family. (160 aa)    
Predicted Functional Partners:
AFZ74927.1
DMT(drug/metabolite transporter) superfamily permease; PFAM: EamA-like transporter family.
 
   
 0.619
AFZ73831.1
Transcriptional regulator; PFAM: AsnC family.
  
 
 
 0.580
AFZ72182.1
Transcriptional regulator; PFAM: HTH domain; TrkA-C domain.
  
  
 0.567
AFZ73510.1
PFAM: Bacterial regulatory protein, arsR family; AsnC family.
  
   
 0.466
AFZ74925.1
Hypothetical protein.
       0.436
AFZ74328.1
PFAM: HTH DNA binding domain.
  
     0.434
AFZ71344.1
Hypothetical protein.
  
   
 0.414
AFZ73930.1
Transcriptional regulator; PFAM: IclR helix-turn-helix domain; AsnC family.
  
   
 0.410
AFZ73464.1
Translation initiation factor 2B subunit, eIF-2B alpha/beta/delta family; PFAM: NUDIX domain; Initiation factor 2 subunit family; Belongs to the eIF-2B alpha/beta/delta subunits family.
  
 
   0.403
Your Current Organism:
Natronobacterium gregoryi
NCBI taxonomy Id: 797304
Other names: N. gregoryi SP2, Natronobacterium gregoryi ATCC 43098, Natronobacterium gregoryi JCM 8860, Natronobacterium gregoryi NCIMB 2189, Natronobacterium gregoryi SP2, Natronobacterium gregoryi str. SP2, Natronobacterium gregoryi strain SP2
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