STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EHM49584.1KEGG: bav:BAV1800 5.9e-53 glutamine amidotransferase; K01951 GMP synthase (glutamine-hydrolysing); Psort location: Cytoplasmic, score: 8.96. (243 aa)    
Predicted Functional Partners:
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
  
 
 0.974
gmk
Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.
   
 
 0.723
EHM49585.1
KEGG: cch:Cag_1938 2.4e-31 Sel1 repeat-containing protein K07126; Psort location: CytoplasmicMembrane, score: 9.82.
       0.636
EHM49586.1
KEGG: pen:PSEEN3732 2.0e-178 ABC transporter, ATP-binding protein K01552; Psort location: Cytoplasmic, score: 9.97.
  
    0.629
EHM55769.1
KEGG: dno:DNO_1110 0. phosphoribosylformylglycinamidine synthase K01952; Psort location: Cytoplasmic, score: 9.26.
  
  
 0.593
EHM49583.1
Putative outer membrane protein A; KEGG: sli:Slin_0746 1.4e-12 V-type H(+)-translocating pyrophosphatase K01507; Psort location: OuterMembrane, score: 10.00.
    
  0.539
EHM56149.1
KEGG: nme:NMB1920 4.8e-113 guaA; GMP synthase K01951; Psort location: Cytoplasmic, score: 9.97.
 
  
 0.537
apt
Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
  
 
 0.531
map
Methionine aminopeptidase, type I; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed; Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
  
    0.528
rplK
Ribosomal protein L11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
   
    0.499
Your Current Organism:
Cardiobacterium valvarum
NCBI taxonomy Id: 797473
Other names: C. valvarum F0432, Cardiobacterium valvarum F0432, Cardiobacterium valvarum str. F0432, Cardiobacterium valvarum strain F0432
Server load: low (30%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.