STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EHM01232.1Hydrolase, NUDIX family; KEGG: hsl:OE1648R 1.3e-14 apa; putative bis(5'-nucleosyl)-tetraphosphatase (asymmetrical). (143 aa)    
Predicted Functional Partners:
EHL95934.1
Pyruvate kinase; KEGG: lbr:LVIS_0765 7.0e-263 pyruvate kinase; K00873 pyruvate kinase; Psort location: Cytoplasmic, score: 9.97.
    
  0.909
EHL95578.1
Non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.
  
 
 0.903
pyrG
CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
    
  0.900
folE
GTP cyclohydrolase I; KEGG: lhe:lhv_1202 6.3e-143 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase/GTP cyclohydrolase I; K00950 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase K01495; Psort location: Cytoplasmic, score: 9.97.
  
 
 0.894
EHL95604.1
Competence/damage-inducible protein CinA domain protein; Belongs to the CinA family.
    
  0.860
EHM01233.1
Guanylate kinase; KEGG: lme:LEUM_1839 9.3e-55 guanylate kinase K00942; Psort location: Cytoplasmic, score: 9.97.
       0.806
EHM01231.1
Na+/H+ antiporter; KEGG: sun:SUN_2183 6.8e-31 cation-transporting P-tyep ATPase; K01537 Ca2+-transporting ATPase; Psort location: CytoplasmicMembrane, score: 10.00.
  
    0.720
EHL95576.1
CBS domain protein.
 
    0.641
EHM01234.1
Transcriptional regulator, Fur family; KEGG: mct:MCR_0333 1.6e-11 fur; ferric uptake regulation protein Fur K03711; Psort location: Cytoplasmic, score: 9.97; Belongs to the Fur family.
       0.568
guaA
GMP synthase domain protein; Catalyzes the synthesis of GMP from XMP.
    
  0.475
Your Current Organism:
Lactobacillus parafarraginis
NCBI taxonomy Id: 797515
Other names: L. parafarraginis F0439, Lactobacillus parafarraginis F0439, Lactobacillus parafarraginis str. F0439, Lactobacillus parafarraginis strain F0439, Lactobacillus sp. oral taxon 418 str. F0439
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