STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EHM00941.1Transcriptional regulator, Sir2 family; KEGG: lre:Lreu_0208 3.8e-74 NAD-dependent deacetylase; K12410 NAD-dependent deacetylase; Psort location: Cytoplasmic, score: 9.26. (238 aa)    
Predicted Functional Partners:
nadD
Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
    
 0.919
nadE
NAD+ synthase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source; Belongs to the NAD synthetase family.
    
 0.915
nadK
NAD(+)/NADH kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
  
 
 0.911
EHM00211.1
Putative NAD(P)(+) transhydrogenase, alpha subunit; KEGG: ooe:OEOE_0369 7.9e-113 NAD/NADP transhydrogenase alpha subunit; K00324 NAD(P) transhydrogenase subunit alpha; Psort location: CytoplasmicMembrane, score: 9.82.
     
 0.898
EHM00212.1
NAD(P)(+) transhydrogenase, alpha-2 subunit family protein; KEGG: bla:BLA_1417 7.9e-26 NAD/NADP transhydrogenase alpha subunit; K00324 NAD(P) transhydrogenase subunit alpha; Psort location: CytoplasmicMembrane, score: 10.00.
     
 0.898
EHM00481.1
Putative cytidine/uridine-specific hydrolase; KEGG: lbr:LVIS_2069 1.1e-131 ribonucleoside hydrolase RihC; K01239 purine nucleosidase; Psort location: Cytoplasmic, score: 8.96.
   
 
 0.897
EHM00243.1
Putative pyrimidine-specific ribonucleoside hydrolase RihB; KEGG: lpl:lp_2591 8.1e-111 purine nucleosidase K01239.
   
 
 0.897
EHM00942.1
Hypothetical protein; Psort location: Cytoplasmic, score: 8.96.
 
     0.848
EHM00938.1
hydroxymethylglutaryl-CoA reductase, degradative; KEGG: lbr:LVIS_0450 7.7e-99 hydroxymethylglutaryl-CoA reductase; K00021 3-hydroxy-3-methylglutaryl-CoA reductase; Belongs to the HMG-CoA reductase family.
  
  
 0.798
EHM00939.1
Hypothetical protein.
  
    0.729
Your Current Organism:
Lactobacillus parafarraginis
NCBI taxonomy Id: 797515
Other names: L. parafarraginis F0439, Lactobacillus parafarraginis F0439, Lactobacillus parafarraginis str. F0439, Lactobacillus parafarraginis strain F0439, Lactobacillus sp. oral taxon 418 str. F0439
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.