STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pdhAPyruvate dehydrogenase E1 component, alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). (373 aa)    
Predicted Functional Partners:
EHM00706.1
Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex.
 0.999
EHM00707.1
Pyruvate dehydrogenase E1 component subunit beta.
 0.999
EHM00705.1
Pyridine nucleotide-disulfide oxidoreductase.
 
 0.996
EHM01090.1
Biotin-requiring enzyme; KEGG: gyc:GYMC61_1519 8.8e-13 dihydrolipoyllysine-residue succinyltransferase K00627; Psort location: Cytoplasmic, score: 9.26.
 
 0.968
EHL98010.1
Pyridine nucleotide-disulfide oxidoreductase; KEGG: lki:LKI_05985 5.3e-178 glutathione reductase; K00383 glutathione reductase (NADPH); Psort location: Cytoplasmic, score: 9.97.
 
 
 0.961
EHL96521.1
Pyridine nucleotide-disulfide oxidoreductase; KEGG: lcz:LCAZH_2595 6.1e-106 glutathione reductase; K00383 glutathione reductase (NADPH); Psort location: Cytoplasmic, score: 9.97.
 
 
 0.961
EHL95934.1
Pyruvate kinase; KEGG: lbr:LVIS_0765 7.0e-263 pyruvate kinase; K00873 pyruvate kinase; Psort location: Cytoplasmic, score: 9.97.
  
 
 0.948
EHM01617.1
KEGG: ooe:OEOE_1723 1.3e-151 2-isopropylmalate synthase K01649; Psort location: Cytoplasmic, score: 9.97; Belongs to the alpha-IPM synthase/homocitrate synthase family.
   
 
 0.932
ldh
L-lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate.
   
 
 0.931
EHM00570.1
Putative NAD-dependent malic enzyme 3; KEGG: ppe:PEPE_1617 7.6e-218 malate dehydrogenase; K00027 malate dehydrogenase (oxaloacetate-decarboxylating); Psort location: Cytoplasmic, score: 9.97.
   
 
 0.926
Your Current Organism:
Lactobacillus parafarraginis
NCBI taxonomy Id: 797515
Other names: L. parafarraginis F0439, Lactobacillus parafarraginis F0439, Lactobacillus parafarraginis str. F0439, Lactobacillus parafarraginis strain F0439, Lactobacillus sp. oral taxon 418 str. F0439
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