STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nadKNAD(+)/NADH kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (270 aa)    
Predicted Functional Partners:
EHM00211.1
Putative NAD(P)(+) transhydrogenase, alpha subunit; KEGG: ooe:OEOE_0369 7.9e-113 NAD/NADP transhydrogenase alpha subunit; K00324 NAD(P) transhydrogenase subunit alpha; Psort location: CytoplasmicMembrane, score: 9.82.
     
 0.953
EHM00212.1
NAD(P)(+) transhydrogenase, alpha-2 subunit family protein; KEGG: bla:BLA_1417 7.9e-26 NAD/NADP transhydrogenase alpha subunit; K00324 NAD(P) transhydrogenase subunit alpha; Psort location: CytoplasmicMembrane, score: 10.00.
     
 0.953
EHM00213.1
Putative NAD(P) transhydrogenase subunit beta; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family.
     
 0.950
nadD
Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
  
 
 0.933
nadE
NAD+ synthase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source; Belongs to the NAD synthetase family.
    
 0.932
EHM00941.1
Transcriptional regulator, Sir2 family; KEGG: lre:Lreu_0208 3.8e-74 NAD-dependent deacetylase; K12410 NAD-dependent deacetylase; Psort location: Cytoplasmic, score: 9.26.
  
 
 0.911
EHM00769.1
RelA/SpoT domain protein; KEGG: lpj:JDM1_1860 4.9e-81 GTP pyrophosphokinase (putative); K07816 putative GTP pyrophosphokinase; Psort location: Cytoplasmic, score: 8.96.
  
    0.874
EHM00767.1
Pseudouridine synthase, RluA family; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family.
  
  
 0.840
EHM00766.1
Hypothetical protein; KEGG: lbr:LVIS_1460 1.5e-77 SAM-dependent methyltransferase; K00563 rRNA (guanine-N1-)-methyltransferase; Psort location: Cytoplasmic, score: 9.97.
       0.779
EHM00765.1
RNA methyltransferase, TrmH family, group 2; Could methylate the ribose at the nucleotide 34 wobble position in tRNA; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
       0.746
Your Current Organism:
Lactobacillus parafarraginis
NCBI taxonomy Id: 797515
Other names: L. parafarraginis F0439, Lactobacillus parafarraginis F0439, Lactobacillus parafarraginis str. F0439, Lactobacillus parafarraginis strain F0439, Lactobacillus sp. oral taxon 418 str. F0439
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