STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EHM00769.1RelA/SpoT domain protein; KEGG: lpj:JDM1_1860 4.9e-81 GTP pyrophosphokinase (putative); K07816 putative GTP pyrophosphokinase; Psort location: Cytoplasmic, score: 8.96. (217 aa)    
Predicted Functional Partners:
EHL98021.1
RelA/SpoT domain protein; KEGG: bde:BDP_1431 5.8e-46 relA2; relA2 GTP pyrophosphokinase; Psort location: Cytoplasmic, score: 8.96.
  
  
 
0.919
nadK
NAD(+)/NADH kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
  
    0.874
EHL95969.1
RelA/SpoT family protein; KEGG: lbr:LVIS_0728 1.9e-166 guanosine polyphosphate pyrophosphohydrolase/synthetase; K00951 GTP pyrophosphokinase; Psort location: Cytoplasmic, score: 8.96.
     
 0.870
EHL95970.1
HD domain protein; KEGG: lbr:LVIS_0728 2.1e-121 guanosine polyphosphate pyrophosphohydrolase/synthetase; K00951 GTP pyrophosphokinase; Psort location: Cytoplasmic, score: 8.96.
     
 0.870
EHM00767.1
Pseudouridine synthase, RluA family; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family.
       0.835
EHM00766.1
Hypothetical protein; KEGG: lbr:LVIS_1460 1.5e-77 SAM-dependent methyltransferase; K00563 rRNA (guanine-N1-)-methyltransferase; Psort location: Cytoplasmic, score: 9.97.
       0.775
EHM00765.1
RNA methyltransferase, TrmH family, group 2; Could methylate the ribose at the nucleotide 34 wobble position in tRNA; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
  
    0.748
mnmE
tRNA modification GTPase TrmE; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
   
    0.700
EHM00764.1
Putative stage III sporulation protein E; KEGG: pen:PSEEN2212 7.2e-103 ftsK; cell division protein FtsK K03466; Psort location: CytoplasmicMembrane, score: 10.00; Belongs to the FtsK/SpoIIIE/SftA family.
       0.663
EHM00770.1
Hypothetical protein; Psort location: Cytoplasmic, score: 8.96.
       0.602
Your Current Organism:
Lactobacillus parafarraginis
NCBI taxonomy Id: 797515
Other names: L. parafarraginis F0439, Lactobacillus parafarraginis F0439, Lactobacillus parafarraginis str. F0439, Lactobacillus parafarraginis strain F0439, Lactobacillus sp. oral taxon 418 str. F0439
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.