STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
clpPEndopeptidase Clp; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. (214 aa)    
Predicted Functional Partners:
clpX
ATP-dependent Clp protease, ATP-binding subunit ClpX; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
 0.996
groS
Chaperonin GroS; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter.
 
 
 0.926
EHL95939.1
Putative chaperone protein ClpB; KEGG: sax:USA300HOU_0933 4.9e-168 clpB; endopeptidase ClpB K03695; Psort location: Cytoplasmic, score: 9.97; Belongs to the ClpA/ClpB family.
   
 
 0.895
groL
Chaperonin GroL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.
 
 
 0.886
EHL99171.1
Negative regulator of genetic competence ClpC/MecB; KEGG: saa:SAUSA300_0510 9.4e-236 clpC; endopeptidase K03696; Psort location: Cytoplasmic, score: 9.97; Belongs to the ClpA/ClpB family.
   
 
 0.877
EHL98543.1
ATPase family; KEGG: snc:HMPREF0837_11672 6.6e-38 clpE; ATP dependent protease K03697; Psort location: Cytoplasmic, score: 9.97.
  
 
 0.871
hrcA
Transcription repressor HrcA; Negative regulator of class I heat shock genes (grpE-dnaK- dnaJ and groELS operons). Prevents heat-shock induction of these operons.
   
  
 0.869
EHL99280.1
Negative regulator of genetic competence ClpC/MecB; KEGG: snc:HMPREF0837_11672 1.8e-234 clpE; ATP dependent protease K03697; Psort location: Cytoplasmic, score: 9.97; Belongs to the ClpA/ClpB family.
   
 
 0.848
EHL98544.1
ATPase, AAA family; KEGG: snc:HMPREF0837_11672 1.8e-131 clpE; ATP dependent protease K03697; Psort location: Cytoplasmic, score: 9.97; Belongs to the ClpA/ClpB family.
   
 
 0.848
EHL97805.1
Putative ATP-dependent Clp protease ATP-binding subunit ClpE; KEGG: sax:USA300HOU_2542 9.4e-220 clp; endopeptidase Clp K04086; Psort location: Cytoplasmic, score: 9.97; Belongs to the ClpA/ClpB family.
   
 
 0.848
Your Current Organism:
Lactobacillus parafarraginis
NCBI taxonomy Id: 797515
Other names: L. parafarraginis F0439, Lactobacillus parafarraginis F0439, Lactobacillus parafarraginis str. F0439, Lactobacillus parafarraginis strain F0439, Lactobacillus sp. oral taxon 418 str. F0439
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.