STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EHM00509.1Beta-lactamase; KEGG: lpl:lp_2021 8.0e-72 pbpX2; serine-type D-Ala-D-Ala carboxypeptidase K01286; Psort location: CytoplasmicMembrane, score: 10.00. (405 aa)    
Predicted Functional Partners:
EHM00514.1
DltD protein; Psort location: CytoplasmicMembrane, score: 9.82.
  
 0.982
EHM00512.1
Putative protein DltB; Could be involved in the transport of activated D-alanine through the membrane.
 
  
 0.967
dltA
D-alanine--poly(phosphoribitol) ligase, subunit 1; Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D- alanyl carrier protein (Dcp) DltC. In an ATP-dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall. Belongs to [...]
 
  
 0.962
guaA
GMP synthase domain protein; Catalyzes the synthesis of GMP from XMP.
     
 0.866
dltC
D-alanine--poly(phosphoribitol) ligase, subunit 2; Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC- carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall.
 
     0.856
EHM00510.1
Hypothetical protein.
  
  
 0.765
EHM00515.1
Beta-lactamase; KEGG: lcb:LCABL_23180 3.1e-38 pbpX1; serine-type D-Ala-D-Ala carboxypeptidase; Psort location: CytoplasmicMembrane, score: 9.97.
 
    
0.597
EHL96161.1
Glycosyl hydrolase family 20, catalytic domain protein; KEGG: asu:Asuc_0859 1.8e-49 glycoside hydrolase family protein; K12373 beta-hexosaminidase; Psort location: Periplasmic, score: 9.44.
 
  
  0.467
EHM00508.1
Hypothetical protein.
  
    0.413
EHM01479.1
Aspartate racemase; KEGG: lsl:LSL_0018 7.1e-80 racX; aspartate racemase K01779; Psort location: Cytoplasmic, score: 8.96; Belongs to the aspartate/glutamate racemases family.
  
  
 0.401
Your Current Organism:
Lactobacillus parafarraginis
NCBI taxonomy Id: 797515
Other names: L. parafarraginis F0439, Lactobacillus parafarraginis F0439, Lactobacillus parafarraginis str. F0439, Lactobacillus parafarraginis strain F0439, Lactobacillus sp. oral taxon 418 str. F0439
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